NETSCHEDULES: INTERNET-BASED GRADUAL SMOKING CESSATION

描述：行为科学协会建议开发和评估 NetSchedules计划，一个基于互联网的渐进吸烟自助计划 停止吸烟者喜欢逐渐减少的方法，但很少成功 逐步减少（SGR）是一种系统的逐步减少方法， 香烟的使用，是有效的。互联网提供了一个理想的工具 分发一个有效的，低成本的，简单易用的吸烟SGR计划， 停止 在第一阶段，将开发一个网站原型， 10-为期一周的可行性研究，有50名受试者。的主要标准 确定可行性将是一个有效的戒烟率> 20%， 吸烟率在统计学上显著降低， 显著减少呼出空气中的一氧化碳。数据变化 整个治疗期间的吸烟率、戒烟尝试、戒断症状， 将对吸烟时间表的遵守情况和计划满意度进行评估。 将评估受试者的定量结果和定性反馈 补充主要结局变量并指导进一步的产品 发展在第二阶段，将开发第二代网站， 在一项大规模试验中进行了评估，并进行了长期随访。 拟议的商业应用： 尽管取得了重大进展，但吸烟仍占美国所有死亡人数的20%，需要继续努力开发和评估戒烟的创新治疗方法。SGR已被证明是自助戒烟的有效和理想的方法。NetSchedules将利用互联网提供一个低成本、简单易用的SGR计划，该计划可能具有广泛的商业吸引力和重大的公共卫生影响。

DESCRIPTION: Behavioral Science Associates proposes to develop and evaluate the NetSchedules program, an Internet-based self-help program for gradual smoking cessation. Smokers prefer gradual reduction methods, but are rarely successful gradual reduction (SGR) a systematic approach to gradual reduction that employs scheduling of cigarettes, is effective. The Internet provides an ideal vehicle for distributing an effective, low-cost, simple to use SGR program for smoking cessation. During Phase I, a prototype of the website will be developed and evaluated in a 10-week feasibility study with 50 subjects. The primary criteria for determining feasibility will be a validated abstinence rate of > 20 percent, statistically significant reductions in smoking rate and statistically significant reductions in expired air carbon monoxide. Data on changes in smoking rate throughout treatment, quit attempts, withdrawal symptoms, adherence to the smoking schedule, and program satisfaction will be evaluated. Quantitative results and qualitative feedback from subjects will be evaluated to supplement the primary outcome variables and guide further product development. During Phase II, a second generation site will be developed and evaluated in a large-scale trial with extended follow-up. PROPOSED COMMERCIAL APPLICATIONS: Despite significant progress, smoking continues to account for 20% of all deaths in the U.S. Continued efforts are needed to develop and evaluate innovative treatment methods for smoking cessation. SGR has been shown to be an effective and desirable method for self-help smoking cessation. NetSchedules will use the Internet to deliver a low-cost, simple to use SGR program that could have broad commercial appeal and a significant public health impact.