Effects of testosterone and oestrogen on body composition

男性化和女性化激素，如睾丸激素和雌激素，分别是控制体内肌肉、脂肪和骨骼数量的重要激素。通过研究患有前列腺癌等疾病的人，这些激素水平被破坏，我们的目标是了解睾丸激素和雌激素如何影响各种身体系统，这可能会导致对脆弱，肥胖和心脏病以及骨质疏松症等重要公共卫生问题的新治疗方法。

Masculinising and feminising hormones such as testosterone and oestrogen respectively are important hormones controlling the amount of muscle, fat and bone in the body. By studying people with conditions such as prostate cancer where these hormone levels are disrupted, we aim to understand how testosterone and oestrogen affects various body systems, which may lead to new treatments for important public health problems of frailty, obesity and heart disease, and osteoporosis.