Electroretinogram recordings of human scotopic dark adaptation following intense bleaching exposures

当一个人暴露在强烈的光照下后，眼睛可能需要几分钟才能恢复完全的灵敏度，就像一个人在阳光明媚的海滩上进入一个黑暗的洞穴时所经历的那样。这个项目将研究在眼睛后部的视网膜细胞中发生的过程，这些过程阻止了强烈光照后视力的瞬间恢复。电子记录将从正常人的眼睛中进行，使用新技术可以监测视网膜中不同类型神经细胞的活动。这项研究将确定眼睛的光探测细胞（视杆细胞和视锥细胞）的活动是如何影响视觉系统中随后的神经细胞的活动的，以及这些活动是如何导致人们在明亮的光线下经历的视力低下的。

After a human subject has been exposed to intense illumination, it can take many minutes for the eye to regain full sensitivity, as one experiences (for example) when entering a dark cave after being out on a bright sunny beach. This project will investigate the processes that occur in the cells of retina lining the back of the eye, that prevent the instantaneous recovery of vision following intense illumination. Electrical recordings will be made from the eyes of normal individuals, using new techniques that allow the activity of different types of nerve cell in the retina to be monitored. The study will determine how it is that events in the light-detector cells of the eye (the rod and cone photoreceptors) influence the activity of subsequent nerve cells in the visual system, and how these events contribute to the poor vision that one experiences following bright lights.