Follow-up--Estimate Incidence of Mobility Disability

本研究的总体目标是评估基线后1至2年的随访状态，基线时年龄为75-85岁的人群被发现有功能限制（EPESE性能组合评分为4-9），但在希伯来家庭康复单位进行的测试中能够行走400米。 需要解决的具体问题包括： 1.在基线时发现能够行走400米的高危老年人中，无法行走400米的发生率是多少？ 2.哪些主要的慢性疾病、损伤和人口统计学特征可以预测意外的行动能力丧失？ 3.在门诊步行400米的客观测试中，可以问什么问题来估算谁将无法步行400米。这种方法学工作可能允许在未来的临床试验中对拒绝来诊所或身体上不能来诊所的人的行动能力残疾状态进行归因。

The overarching goals of this research are to evaluate follow-up status, 1 to 2 years after baseline, of a cohort of persons aged 75-85 at baseline who were found to have functional limitations (EPESE performance battery score of 4-9) but who were able to walk 400 meters in a test done in the Hebrew Home rehabilitation unit. Specific questions to be addressed include: 1.What is the incidence of inability to walk 400 meters in at-risk older persons who were found to be able to walk this far at baseline? 2.What are the main chronic diseases, impairments, and demographic characteristics which predict incident mobility loss? 3.What questions can be asked to impute who will be unable to walk 400 meters in an objective test of walking this distance in the clinic. This methodologic work may allow for the imputation of mobility disability status in persons in a future clinical trial who refuse to come into the clinic or are not physically capable of coming to the clinic.