CONFERENCE ON ARTERIOSCLEROSIS AND VASCULAR BIOLOGY

动脉硬化、血栓形成和血管生物学会议将于2000年5月20日至22日在科罗拉多州的布鲁姆菲尔德/丹佛举行，为期两天半。本次会议旨在成为一年一度的会议，重点关注动脉硬化(脂类和脂蛋白)、血栓形成和血管生物学领域的新出现的研究。这次会议由美国心脏协会动脉硬化、血栓和血管生物学委员会主办，第一年由北美血管生物学组织协办。这次会议的主要目标是将动脉硬化、血栓和血管生物学研究社区内的不同学科聚集在一起，使研究人员能够交换和传播信息，并探索跨学科感兴趣的领域。长期以来，这些学科一直被视为独立的实体，但实际上，脂质和脂蛋白功能与血栓和血管壁事件交织在一起，反之亦然。该计划旨在鼓励这些学科之间的交叉受精，通过在非正式环境中检查脂类和脂蛋白、血栓形成和血管生物学方面的新领域和新兴领域。热点话题和全体会议旨在促进血管生成、动脉粥样硬化中的PPAR、一氧化氮功能、高密度脂蛋白代谢中的ABC1基因、血管疾病的分子遗传学和血管壁细胞生物学等领域的跨学科讨论和互动。每个具有代表性的领域，即动脉硬化、血栓形成和血管生物学，计划举行的特别会议将提供口头介绍摘要的机会，每次会议首先由该领域的一名专家就这一专题进行主旨演讲。动脉硬化会议涵盖转基因和腺病毒模型领域，以研究脂蛋白代谢、动脉粥样硬化中的高密度脂蛋白、饮食和基因对血脂异常的影响，以及脂肪酶在动脉粥样硬化中的作用。血栓形成会议涉及蛋白C途径、整合素生物学、血小板信号以及纤溶中的体液和细胞因子。血管生物学课程包括血管内皮细胞功能、血管平滑肌细胞病理生物学、血管自身调节和重塑以及血管疾病中的炎症。这次会议将促进动脉硬化、血栓形成和血管生物学之间更紧密的联系，并为研究人员提供机会讨论新的突破性信息。由于在脂类和脂蛋白、血栓形成和血管生物学领域培养全面发展的新研究人员的重要性，一个主要目标是鼓励年轻科学家参加会议。

The Conference on Arteriosclerosis, Thrombosis and Vascular Biology is a two and one-half day meeting, May 20-22, 2000, to be held in Broomfield/Denver, Colorado. This meeting is designed to be an annual meeting that will focus on new emerging research in the areas of arteriosclerosis (lipids and lipoproteins), thrombosis and vascular biology. The meeting is sponsored by the Council on Arteriosclerosis, Thrombosis and Vascular Biology of the American Heart Association and in its first year is co- sponsored by the North American Vascular Biology Organization. The major goal of this conference is to bring together diverse disciplines within the Arteriosclerosis, Thrombosis and Vascular Biology research communities to allow investigators to exchange and disseminate information and to explore areas of cross- disciplinary interest. These disciplines have long been treated as separate entities yet in reality lipid and lipoprotein functions are interwoven with thrombotic and vascular wall events and vice versa. The program is designed to encourage cross- fertilization between these disciplines by examining new and emerging areas in lipids and lipoproteins, thrombosis and vascular biology in an informal setting. Hot Topics and Plenary sessions have been designed to stimulate interdisciplinary discussions and interactions in the areas angiogenesis, PPARs in atherosclerosis, nitric oxide function, abc1 gene in HDL metabolism, molecular genetics of vascular disease, and cell biology of the vessel wall. Special sessions planned by each of the representative areas, i.e., arteriosclerosis, thrombosis and vascular biology, will provide an opportunity for oral presentations of abstracts and each session begins with a keynote talk on the topic to be given by an expert in the field. The arteriosclerosis sessions cover the areas of transgenic and adenovirus models to study lipoprotein metabolism, HDL in atherosclerosis, diet and gene contribution to dyslipidemias, and lipases in atherosclerosis. The thrombosis sessions address the areas of protein C pathways, integrin biology, platelet signaling, and humoral and cellular factors in fibrinolysis. The vascular biology sessions include endothelial cell function, smooth muscle cell pathobiology, vascular autoregulation and remodeling, and inflammation in vascular disease. The conference will foster stronger links between arteriosclerosis, thrombosis and vascular biology and provide an opportunity for investigators to discuss newly breaking information. Because of the importance for developing well-rounded new investigators in the areas of lipids and lipoproteins, thrombosis and vascular biology, a major objective is to encourage young scientists to attend the conference.