PULMONARY AND CARDIOVASCULAR DEVELOPMENT TRAINING GRANT

这项心肺生物学培训补助金的目标是建立一个培训计划，通过为辛辛那提大学研究生项目中的三名博士后助理和三名博士后候选人提供津贴，加强哺乳动物胚胎和围产期生物学关键方面的基础研究培训。该计划在很大程度上借鉴了分子、发育和细胞生物学研究的综合、创新和成熟的研究生计划，并受益于由NHLBI支持的心肺分子生物学卓越中心开发的相关计划。该计划确定并招募有前途的年轻博士和博士后候选人，他们将完成博士学位或博士后培训计划。将特别关注少数民族的招募和该计划的医学博士候选人。博士后实习生将拥有医学博士或博士学位，或两者兼有，并将在竞争的基础上被选中。科学指导、职业发展和课程工作将在辛辛那提大学医学院的研究生课程中获得，培训教师将参加该课程。该项目汇集了24名具有使用当代分子和细胞策略的经验的知名研究人员，他们在儿童医院研究基金会和辛辛那提大学医学院研究肺、心脏和血液的发育生物学。这些教师都有共同的研究兴趣，通常在发展科学方面有着悠久的合作历史。主要主题包括：哺乳动物胚胎发育过程中基因表达的研究，基因打靶，以及利用转基因小鼠研究发育中小鼠的基因功能和调控。赠款将包括由首席调查员、执行委员会、外部和内部咨询委员会组成的行政核心。正在进行的研究将包括一门侧重于科学行为中的伦理问题的课程。博士前实习生将在辛辛那提大学医学院的发育生物学研究生计划、生物医学学位计划、解剖学和细胞生物学系或分子遗传学、生物化学和微生物学系获得博士学位。定期的研究会议和几个相关的研讨会系列进一步加强了该方案。执行委员会将每年审查每名受训人员的进展情况。

The goal of this Training Grant in Pulmonary and Cardiovascular Biology is to establish a training program for the enhancement of basic research training in critical aspects of mammalian embryonic and perinatal biology by providing stipends for three postdoctoral associates and for three predoctoral candidates within the University of Cincinnati Graduate Programs. The program draws heavily upon integrated, innovative, and established Graduate Programs for the study of molecular, developmental, and cell biology and benefits from related programs developed at the Center of Excellence in Molecular Biology of Heart Lung, support by the NHLBI. This program identifies and recruits promising young doctoral and postdoctoral candidates who will complete their doctoral degree, or a postdoctoral training program. Special attention will be given to recruitment of minorities and to M.D. candidates for this program. Postdoctoral trainees will have the M.D. or Ph.D. degree, or both, and will be selected on a competitive basis. Scientific guidance, career development and course work will be obtained within the graduate programs at the University of Cincinnati College of Medicine in which the training faculty participate. The program has brought together 24 distinguished and well-established investigators with experience using contemporary molecular and cellular strategies to study the developmental biology of lung, heart and blood at Children's Hospital Research Foundation and at the University of Cincinnati College of Medicine. These faculty share research interests generally having a long history of collaboration in developmental science. The major themes include: study of gene expression during mammalian embryogenesis, gene targeting, and the use of transgenic mice to study gene function and regulation with the developing mouse. The grant will include an administrative core consisting of the Principal Investigator, Executive Committee, external and internal Advisory Boards. Ongoing studies will include a course focused to ethical issues in the conduct of science. Predoctoral trainees will obtain their Ph.D. degrees in the Developmental Biology Graduate Program, Biomedical Sciences Degree Program, Department of Anatomy and Cell Biology, or Department of Molecular Genetics, Biochemistry and Microbiology, at the University of Cincinnati College of Medicine. Regular research meetings and several pertinent seminar series further enhance the program. Progress of each trainee will be reviewed annually by the Executive Committee.