Pilot and Feasibility Core

项目概要：“试点和可行性方案”将促进新的和早期的发展， 阶段调查员，并为创新和尖端项目提供种子支持，以迅速推进 个性化囊性纤维化治疗和研究中心的科学和研究兴趣 （PCFC）。 该计划旨在支持与个性化CF相关的高度创新的研究 医学和促进新的和早期阶段的研究人员过渡，以获得校外资助 并支持他们的个人研究计划。我们有几个新的和早期阶段的调查员， CCHMC致力于个性化CF医学研究。他们目前没有NIH RO 1 资助，但也有其他类型的资助，例如NIH K型奖和RO 3奖，以及私人资助 地基（即，帕克B弗朗西斯，CFF，美国心脏协会（AHA），辛辛那提儿童研究 基金会（CCRF），仅举几例）。此外，我们还将鼓励那些愿意 将他们的研究计划扩展到个性化CF医学研究。PCFC的目的是 鼓励这些研究人员开发一个创新的研究计划，在 CF/CFTR相关基础研究领域，并开发个性化CF医学的转化计划 主题.

PROJECT SUMMARY: The “Pilot and Feasibility Program” will foster the development of new and early stage investigators and to provide seed-support for innovative and cutting edge projects to rapidly advance the scientific and research interests of the Personalized Cystic Fibrosis Therapy and Research Center (PCFC). This program is designed to support highly innovative research relevant to personalized CF medicine and to facilitate the transition of new and early stage investigators to obtain extramural funding and to sustain their individual research program. We have several new and early stage investigators at CCHMC who are passionate in personalized CF medicine research. They currently do not have NIH RO1 funding, but have other types of funding such as NIH K-type award and RO3 award, support from private foundations (i.e., Parker B Francis, CFF, American Heart Association (AHA), Cincinnati Children’s Research Foundation (CCRF), to name a few). In addition, we will also encourage established investigators who wish to extend their research program into personalized CF medicine research. It is the intention of the PCFC to encourage these investigators to develop an innovative research program that would blaze new trails in the area of CF/CFTR related basic research and develop translational program with personalized CF medicine theme.