CROSS NATIONAL ER ANALYSIS OF ALCOHOL AND CASUALTY

描述：该项目将汇编，合并和分析有关酒精的数据， 来自30个急诊室（ER）的损伤，代表6个研究中的15个ER研究 包括美国在内的国家，墨西哥、加拿大、澳大利亚、意大利和西班牙。 这些研究使用了具有统一科学严谨性的类似方法， 共有超过21，000名患者。拟议的分析将超越 检查个人和事件层面的变量，包括社会和 与ER服务相关的文化因素和组织指标。 具体目标包括：1）检查的异同 在ER研究中，关于：a）损伤风险的综合指标; B）关于一般伤害的个别危险因素的影响的调查结果， c）在活动中饮酒的影响; d） 饮酒致伤; e）酒精相关损伤的流行病学概况; 制定和规范文化、 影响分配的组织和行政因素 酒精相关损伤以及危险因素与损伤率的关系 在ER研究中;和，3）开发和测试比较模型：a）风险 伤害因素; B）饮酒对伤害风险的急性影响; c） 饮酒与伤害的因果关系; d） 与酒精相关的伤害与个人， 组织和文化特征。分析技术将包括 荟萃分析（目标1）和合并回归，因果建模和多水平 建模（目标3）。该项目将提供关于以下方面的第一批可用数据： 不同类型的伤害的性别特有的伤害风险，有助于 关于建议的“安全”饮酒水平的知识体系正在发展。 该项目还将告知目前对下列风险的估计： 酒精和伤害交叉伤害类型，对建立预防很重要 优先事项，并将提供一个档案，酒精涉及的伤害， 将作为制定持续监测系统的基础， 预防和政策制定。该项目还将提供新的数据， 影响酒精与伤害因果归因的情境因素 （对制定有效的干预战略很重要），并将提供 第一个关于社会文化差异相互作用的比较数据， 饮酒和医疗保健，以及组织和行政差异， 各国的急诊服务提供系统， 影响ER治疗寻求的个人饮酒特征， 急诊室病例中的酒精负担，以及基于酒精和损伤的相关性 在ER研究中。

DESCRIPTION: This project will compile, merge and analyze data on alcohol and injury from 30 emergency rooms (ERs), representing 15 ER studies across six countries, including the U.S., Mexico, Canada, Australia, Italy and Spain. These studies used similar methodologies with uniform scientific rigor, and together include over 21,000 patients. The proposed analysis will go beyond the examination of individual and event-level variables, to include social and cultural factors and organizational indicators pertaining to ER services. Specific aims include: 1) an examination of the similarities and differences across ER studies with respect to: a) aggregate measures of risk of injury; b) findings on the impact of individual risk factors for injury in general and by type; c) the impact of drinking-in-the-event; d) casual attribution of drinking to injury; e) epidemiologic profiles of alcohol-related injury; development and standardization of operational measures of cultural, organizational and administrative factors which affect the distribution of alcohol-related injuries and the association of risk factors and injury rates in ER studies; and, 3) development and testing comparative models of: a) risk factors for injury; b) acute impact of drinking on injury risk by type; c) causal attribution of drinking to injury; d) epidemiologic profiles of alcohol-related injury in relation to a combination of individual, organizational and cultural characteristics. Analytic techniques will include meta-analysis (Aim 1) and merged regressions, causal modeling and multilevel modeling (Aim 3). The project will provide the first available data on gender-specific risk of injury for various types of injury, contributing to the developing body of knowledge on recommended "safe" levels of drinking. The project will also inform current estimates of the attributable risk of alcohol and injury cross injury type, important for establishing prevention priorities, and will provide a profile for alcohol-involved injuries, which will serve as a basis for developing an on-going monitoring system to inform prevention and policy development. The project will also provide new data on contextual factors affecting causal attribution of alcohol and injury (important for tailoring effective intervention strategies), and will provide the first comparative data on the interaction of socio-cultural differences in drinking and medical care, and organization and administrative differences in ER services delivery systems across countries, with injury, demographic and individual drinking characteristics which affect ER treatment seeking, the alcohol burden in ER caseloads, and associations of alcohol and injury based in ER studies.