PATHOBIOLOGY OF MUCOSAL/EPITHELIAL DISEASE

这份申请是为一个新的机构NRSA提供支持，以支持最初两名和随后五名医学博士和博士博士后研究员的培训。尽管这是一项新的计划，但过去几位培训教师在培训这类个人时表现出了高度的互动性，作为一个整体，在过去十年里，他们在培训现在担任学术或研究职务的个人方面取得了极大的成功。例如，在过去五年内退出培训计划的受训者表现出对研究的持续参与(大约70%的受训者投入研究的努力超过50%)。该计划的广泛目标是提供面向问题的粘膜疾病病理生理学研究的多学科培训，特别是极化上皮和消化道疾病。培训教师由20名研究人员组成，他们拥有与这一研究领域相关的独立、资助的研究计划。该学院提供现代分子、免疫学和细胞生物学方法方面的专业知识，用于研究疾病的病理生理学。特别强调上皮生物学和免疫学，因为它与上皮生物学和免疫学有关，因为它与消化道等部位的上皮生物学有关。培训计划的结构旨在促进参与培训的教员之间的互动，并为受训人员提供访问所有实验室及其大量资源的机会。学员是从全国研究生和临床课程中挑选出来的，重点是识别代表性不足的少数民族。培训方案的主要组成部分是学员在其选择的实验室进行的独立研究。通过参加研究会议、期刊俱乐部和正式研讨会，以及参加主要由该培训计划的教职员工提供的课程，进一步加强了培训体验(即，该培训计划的教职员工在埃默里大学医学院的研究生教育计划中具有高度的互动性)。

This application is for a new institutional NRSA to support the training of initially two and subsequently five M.D. and Ph.D. Postdoctoral Fellows. Although a new program several of the training faculty have been highly interactive in training such individuals in the past and faculty as a whole has been highly successful in training individuals over the last ten years who now hold academic or research appointments. For example trainees who have left the program of training within the last five years show significant continuing involvement in research (approximately 70% have greater than 50% effort devoted to research). The broad objective of this program is to provide multi-disciplinary training in problem oriented research on the pathophysiology of mucosal disease with special reference to polarized epithelial and alimentary tract disorders. The training faculty consists of twenty investigators with independent, funded research programs related to this area of study. The faculty provides expertise in modern molecular, immunologic and cell biologic approaches for studying pathophysiology of disease. There exists particular emphasis on epithelial biology and immunology as it relates to epithelial biology and immunology as it relates to epithelial biology at sites such as the alimentary tract. The structure of the training program is designed to promote interactions among participating faculty and to provide trainees access to all of the laboratories and their considerable resources. Trainees are selected from graduate and clinical programs nationwide with an emphasis on identifying under-represented minorities. The major component of the training program is independent research carried out by trainees in their laboratories of choice. The training experience is further enhanced by attendance at research conferences, journal clubs and formal seminars as well as attendance in coursework largely provided by the faculty of this training program (i.e. the faculty of the training program are highly interactive in the graduate education program at Emory University School of Medicine).