Deafness Research Foundation Clinical Research Workshop

本申请寻求对为期5天的密集临床研究会议的支持，会议将介绍临床研究科学的最新进展，并将这些知识应用于实际指导经验中，以用于研究设计和方案开发。会议需要解决在沟通疾病和障碍方面工作的训练有素的研究临床医生的短缺，他们需要满足转化临床研究和耳鼻咽喉头颈外科和沟通障碍的循证实践的需求。会议将于2003年4月7日至12日在马里兰州波托马克的博尔格会议中心举行。分子生物学和遗传学的进展为制定新的和改进的诊断、治疗和预防措施以防治人类传播疾病和失调提供了途径。然而，除非临床研究人员， 特别是那些有能力进行转化研究的人，进行必要的研究，以证明有效性的证据，将这些进展从板凳带到床边。现有可行的研究项目太少，无法满足这些需求。这一不足是由于：1）训练有素、经验丰富和有指导的研究人员数量不足; 2）缺乏一个可行的国家临床研究系统，临床科学家网络可以在其中开展所需的临床研究项目。拟议的会议将包括全体讲座，小组讨论和小组研讨会。教师是临床研究方法和内容领域的专家。与会者将是沟通疾病和障碍的医生和其他临床医生，如听力学家和言语/语言病理学家。奖学金将提供给与会者与证明承诺 临床研究，证明了初步的研究项目和支持信在他们的应用程序。

This application seeks support for a 5 day intensive clinical research conference in which to present the latest advances in the science of clinical investigation and apply this knowledge within a practical mentored experience for the purposes of study design and protocol development. The conference is needed to address the shortage of trained research clinicians working in communication diseases and disorders, who are required to meet the demands of translational clinical research and the evidence-based practice of Otolaryngology-Head and Neck Surgery and Communication Disorders. The conference will be held April 7-12, 2003 at the Bolger Conference Center, Potomac, Maryland. Advances in molecular biology and genetics have provided a pathway for the development of new and improved diagnostic, therapeutic and preventive measures to combat human communication diseases and disorders. However, patients cannot benefit from these basic science advances unless clinical researchers, particularly those with the ability to conduct translational research, perform the studies necessary to demonstrate evidence of effectiveness that will bring these advances from the bench to the bedside. Too few viable research projects exist to meet these needs. This shortfall is due to 1) inadequate numbers of trained, experienced, and mentored investigators; and 2) the absence of a viable national clinical research system in which networks of clinical scientists can carry out the needed clinical research projects. The proposed conference will consist of plenary lectures, panel discussions, and small group workshops. The faculty members are experts in clinical research methods and in content areas. Attendees will be physicians and other clinicians in communication diseases and disorders, such as audiologists and speech/language pathologists. Fellowships will be available for attendees with a demonstrated commitment to clinical research as evidenced by a preliminary research project and letters of support in their applications.