Resource and QOL Consequences of Lung Cancer Screening

描述(由申请人提供)：本提案的主要目的是为应聘者提供实现以下目标的手段、指导和结构。中间目标是衡量使用低剂量螺旋计算机断层扫描(CT)筛查肺癌的心理、生活质量和资源效应，以及影响遵守后续建议的因素。长期目标是成为一名独立的卫生服务研究人员，专注于癌症筛查计划的评估和促进癌症筛查中的个人决策。应聘者将进一步发展和利用心理测量和分析、癌症流行病学和癌症筛查技术以及通过医疗索赔数据库评估医疗资源利用的研究技能。职业发展计划将包括正式的课程工作，与特定方法学领域的专家的教程，临床 通过导师和国家癌症研究所癌症预防和控制暑期课程、会议和研讨会以及研究进行培训。 这项拟议研究的主要目标是衡量参与肺癌筛查计划的个人的心理和资源利用后果，以及对筛查后续建议的遵守情况。目前尚不确定筛查肺部CT的临床益处。然而，筛查CT在所有筛查的个体中检测到大约40%的异常。为了评估和改进筛查肺部CT计划，并促进有关筛查的知情决策，确定筛查的非临床效果是至关重要的。这项拟议的研究将从NCI资助的关于筛查肺部CT临床结果的孢子项目中招募患者(Joel Weissfeld，P.I.，匹兹堡肺筛查研究)。心理特征和医疗使用情况的自我管理调查，医疗索赔数据，以及PLuSS研究的数据将随着时间的推移而收集。拟议的K07研究将确定1)参与肺癌筛查的心理和资源影响，2)这些影响如何随筛查结果和个人特征而变化，3)个人是否坚持筛查后推荐的后续行动，以及哪些因素影响不遵守。

DESCRIPTION (provided by applicant): The primary purpose of this proposal is to provide the candidate with the means, mentorship and structure to achieve the following goals. The intermediate goal is to measure the psychological, quality of life and resource effects of screening for lung cancer using low dose spiral computed tomography (CT), as well as factors affecting adherence to follow up recommendations. The long term goal is to become an independent health services researcher focusing on evaluation of cancer screening programs and promotion of individual decision making in cancer screening. The candidate will further develop and utilize research skills in psychological measurement and analysis, cancer epidemiology and cancer screening techniques, and assessment of health care resource utilization through medical claims databases. The career development program will incorporate formal course work, tutorials with experts in specific methodological fields, clinical training through preceptorships and the National Cancer Institute Cancer Prevention and Control summer course, conferences and seminars, and research. The major goal of the proposed research is to measure the psychological and resource utilization consequences for individuals participating in a lung cancer screening program, and adherence to follow up recommendations from screening. The clinical benefits of screening lung CT are as yet uncertain. However, screening CT detects abnormalities in approximately 40% of all screened individuals. To evaluate and improve screening lung CT programs, and to promote informed decision making concerning screening, it is essential to determine the non-clinical effects of screening. The proposed research will recruit patients from an NCI-funded SPORE project on the clinical outcomes of screening lung CT (Joel Weissfeld, P.I., Pittsburgh Lung Screening Study). Self-administered surveys of psychological characteristics and medical care use, medical claims data, and data from the PLuSS study will be collected over time. The proposed K07 research will determine 1) the psychological and resource effects of participating in lung cancer screening, 2) how these effects vary with screening results and individual characteristics, and 3) whether individuals adherence to recommended follow up after screening and what factors affect non-adherence.