Interferometric biosensor based on guided-mode resonances

对用于护理点应用和个性化医疗的光子生物传感器的研究是由对高灵敏度，低成本和可靠技术的需求驱动的。在最敏感的模式中，干涉测量提供了特别高的性能，但通常缺乏所需的操作简单性和鲁棒性。该项目研究了一种基于导模谐振的共路干涉传感器，以将联合收割机的高性能与固有稳定性相结合。我们看到了在抗生素指导中的应用，以及利用本质上简单而强大的传感模式检测临床或环境相关小分子的可能性。

Research towards photonic biosensors for point-of-care applications and personalized medicine is driven by the need for high-sensitivity, low-cost and reliable technology. Amongst the most sensitive modalities, interferometry offers particularly high performance but typically lacks the required operational simplicity and robustness. The project investigates a common-path interferometric sensor based on guided-mode resonances to combine high performance with inherent stability. We see applications in antibiotic guidance and possibilities for detecting clinically or environmentally relevant small molecules with an intrinsically simple and robust sensing modality.