Immunology Physician Scientist Training Grant

描述（由申请人提供）：这是一份美国国立卫生研究院T32机构培训拨款申请，申请的是贝勒医学院的一个新项目，重点是将医生培训为免疫学学科的研究人员。学员将从ACGME/RRC批准的贝勒过敏和免疫学以及风湿病学双轨培训项目的大量优秀申请者中招募和选择。在完成过敏/免疫学和风湿病学一年的临床培训后，每年将选择一名学员进入拟议的T32培训计划，进行为期三年的严格科学培训。根据他们在研究和教学方面的卓越表现，我们精心挑选了15名终身教职教师作为导师。受训者将参加研究生院课程和贝勒国立卫生研究院K30支持的临床研究医师课程，以获得基础科学和免疫学知识的坚实基础，进行临床研究的原则，以及研究的道德行为。受训者将在假设驱动的研究、编写和出版手稿、在国家会议上发言、准备拨款申请、教学和指导技能以及学术生涯发展等方面得到全面指导。这些导师是从贝勒大学新的多学科炎症生物学中心的40多名教师中挑选出来的，他们提供了一个高度互动的研究人员的关键数量，包括研究生、医科学生、博士博士后和医学博士博士后。导师提供细胞因子结构和功能、趋化因子生物学、粘附分子、信号转导和信号终止、基因激活、金属蛋白酶和组织重塑、细胞免疫学和免疫调节、小鼠炎症模型、设计流行病学和临床试验结果分析的有效工具等方面的培训机会。该培训计划的目标是培养将成为未来学术领袖的免疫学内科科学家。

DESCRIPTION (provided by applicant): This is an NIH T32 institutional training grant application for a new program at Baylor College of Medicine focused on the training of physicians as investigators in the discipline of immunology. Trainees will be recruited and selected from a large pool of outstanding applicants to the ACGME/RRC approved Baylor dual track training programs in allergy and immunology and in rheumatology. One trainee will be selected to enter the proposed T32 training program each year for three years of rigorous scientific training after they have completed one year of clinical training in allergy/immunology and rheumatology. Fifteen tenure track faculty have been carefully selected to serve as mentors, based on their excellence in research and teaching. Trainees will enroll in graduate school courses and Baylor's NIH K30 supported physician scientist course in clinical investigation to acquire a sound fund of knowledge in basic science and immunology, the principles of conducting clinical research, and the ethical conduct of research. Trainees will be comprehensively mentored in hypothesis driven research, preparation and publication of manuscripts, presentations at national meetings, preparation of grant applications, skills for teaching and mentoring, and academic career development. The mentors are selected from over 40 faculty within the new multidisciplinary Biology of Inflammation Center at Baylor, and provide a highly interactive critical mass of investigators with diverse trainees comprised of graduate students, medical students, Ph.D. postdocs and M.D. postdocs. Mentors provide training opportunities in cytokine structure and function, chemokine biology, adhesion molecules, signal transduction and termination of signaling, gene activation, metalloproteases and tissue remodeling, cellular immunology and immunoregulation, murine models of inflammation, and design of valid tools for epidemiology and clinical trial outcome analysis. The goal of the training program is to develop immunology physician scientists who will serve as the academic leaders of the future.