Training Program in Chemosensory Neuroscience

描述（由申请人提供）：过去十年出现了惊人的增长 在化学感应研究中， 领域味觉和嗅觉系统提供了独特的机会， 神经生物学的基本问题。化学感官的研究范围从 嗅觉和味觉受体的分子生物学鉴定， 嗅觉和味觉功能障碍的治疗。令人兴奋的发现是 新的和迅速变化的技术的应用和许多 博士后研究人员正在从其他学科进入这一领域。这些 研究人员带来了分子生物学的技术和方法， 发育神经科学、生物物理学、临床医学等学科 来研究化学意义上的问题。比以往任何时候都更是如此 重要的是保持多学科的培训计划，可以提供这些 科学家与该领域的基本知识，这将使他们能够更多地 清晰而准确地指导和解释他们的研究。本申请寻求 继续支持四名博士后研究员的研究培训。的 培训教师在化学感官方面有完善的研究计划 以及神经科学的相关领域，这是由美国国立卫生研究院和其他 社.这些教师采用广泛的技术，包括 分子，电生理，超微结构，神经化学， 药理学，免疫学和心理物理学，使用的制剂， 从体外组织培养和切片到表现良好的动物。除了 实验室研究培训，博士后研究员参加双周一次的 Chemosensory Journal Club和访问神经科学家的定期研讨会系列 在化学感官和其他领域。除了一名培训教员外， 位于解剖学与神经生物学系，那里有一个主要的重点 化学感应研究这个小组有一个既定的记录，培训许多 化学感官和神经科学其他领域的杰出研究人员。 在本资助期内获得资助的八名博士后研究员 非常富有成效;三个已经进入终身教职。的 培训教师是神经科学跨学科计划的一部分， 由解剖学和神经生物学主席指导。解剖学系& 神经生物学是围绕新装备的核心实验室，提供 学生和博士后研究员具有高度的互动性， 分享设备、技术和想法。正是这一能力的力量 他们广泛的实验方法，他们的高度 智力合作，提供了一个独特的和令人兴奋的多学科 培养博士后研究员在化学意义上。

DESCRIPTION (provided by applicant): The last decade has seen spectacular growth in chemosensory research and increased recognition of the importance of this field. The taste and olfactory systems provide unique opportunities to address fundamental issues in neurobiology. Research in the chemical senses ranges from the molecular biology of olfactory and taste receptors to the identification and treatment of olfactory and gustatory dysfunction. Exciting discoveries are emerging from the application of new and rapidly changing technologies and many postdoctoral researchers are entering this field from other disciplines. These investigators bring the techniques and approaches of molecular biology, developmental neuroscience, biophysics, clinical medicine, and other disciplines to research issues in the chemical senses. More than ever before, it is important to maintain multidisciplinary training programs that can provide these scientists with the basic knowledge of this field, which will allow them to more clearly and precisely direct and interpret their studies. This application seeks to renew support for research training for four postdoctoral fellows. The training faculty have well-established research programs in the chemical senses and related areas of neuroscience, which are heavily funded by the NIH and other agencies. These faculty employ a wide spectrum of techniques, including molecular, electrophysiological, ultrastructural, neurochemical, pharmacological, immunological, and psychophysical, using preparations ranging from in vitro tissue culture and slices to behaving animals. In addition to laboratory research training, postdoctoral fellows participate in a biweekly Chemosensory Journal Club and regular seminar series by visiting neuroscientists in the chemical senses and other areas. All but one of the training faculty are housed in the Department of Anatomy & Neurobiology, where there is a major focus on chemosensory research. This group has an established record of training many outstanding researchers in the chemical senses and other areas of neuroscience. The eight postdoctoral fellows supported during the current funding period have been very productive; three have moved into tenure-track faculty positions. The training faculty are part of an interdisciplinary Program in Neuroscience, which is directed by the Chair of Anatomy & Neurobiology. The Department of Anatomy & Neurobiology is organized around newly equipped core laboratories, which provide the students and postdoctoral fellows with a high degree of interaction and sharing of equipment, techniques and ideas. It is the strength of this faculty, their wide range of experimental approaches, and their high degree of intellectual collaboration that provides a unique and exciting multidisciplinary training program for postdoctoral fellows in the chemical senses.