CORE--BIOSTATISTICS AND DATA MANAGEMENT

核心C是这个PPG的新核心。此前，通过行政核心核心A向PPG调查人员提供统计相关服务。由于对这类服务的需求增加，核心C现在是一个独立的核心。核心C将主要侧重于生物统计和数据管理(BDM)，包括计量。然而，Core C还结合了“建模”和图像分析的分析组件。我们的目标是确保将适当的统计专业知识整合到每个项目中，从开始(例如，设计、功率分析)到实施(例如，测量评估)，再到完成(统计分析、解释和报告)。核心C将提供以下服务：1.协助设计研究。BDM团队的一个主要目标是使研究人员能够在开始他们的主要项目或新的子项目之前获得关于实验设计的建议。2.管理由PPG生成的所有数据的电子数据库，确保安全储存和备份，确保录入的质量和准确性，并及时提供数据文件以供后续分析。3.与调查人员和CORE合作，评估和维护PPG中使用的测量的可靠性和有效性。4.协助确定、获取和使用软件进行统计分析和相关任务。5.就调查员自己选择进行的统计程序的选择、实施和解释进行协商。6.根据需要进行更复杂的统计分析(如模拟研究、混合模型)。7.就编写手稿的统计和相关方面进行合作。8.促进更多地发展和利用建模和图像分析程序方面的专门知识。包括5名博士统计数据分析师在内的8名科学家将通过Core C提供支持。通过依靠一支拥有不同专业领域的统计数据分析师团队，我们可以在几乎任何统计分析领域支持这些项目。

Core C is a new core to this PPG. Previously, statistically related services were offered to PPG investigators through Core A, the administrative core. Core C is now an independent core, due to increased demand for such services. Core C will focus primarily on biostatistics and data management (BDM) including measurement. However, Core C also incorporates analytical components of "modeling" and image analysis. Our objective is to insurer that appropriate statistical expertise is integrated into each project from inception (e.g., design, power analysis), to implementation (e.g., measurement evaluation), to completion (statistical analysis, interpretation, and reporting). Core C will provide the following services: 1. Assistance in the design of studies. A major goal of the BDM team is to enable investigators to obtain advise on experimental design before they begin their primary projects or new sub-projects. 2. Management of an electronic database of all PPG-generated data, ensuring secure storage and back up, quality and accuracy of entry, and timely provision of data files for subsequent analyses. 3. Collaboration with investigators and Core in evaluating and maintaining the reliability and validity of measured used in the PPG. 4. Assistance in identifying, obtaining, and using software for statistical analysis and related tasks. 5. Consultation on the choice, implementation, and interpretation of statistical procedures that investigators choose to conduct themselves. 6. Conduct of more complex statistical analyses as needed (e.g. simulation studies, mixed models). 7. Collaboration on preparing statistical and related aspects of manuscripts. 8. Fostering greater development and use of expertise in modeling and image analysis procedures. Eight scientists including five Ph.D. statistician-data analysts will provide support through Core C. By relying on a team of statistician-data analysts with diverse areas of specialization, we can support the projects in virtually any area of statistical analysis.