CORE--TRANSGENIC ANIMAL

描述：（申请人描述）转基因动物/胚胎干细胞 细胞共享设施于1991年启动，并成为癌症中心共享 1995年的设施。其目的是为癌症中心的研究人员提供 无病原体转基因小鼠，具有高标准的质量控制， 效率该服务还提供咨询和咨询，以首次 使用者、股票的再衍生、冷冻保存和相关技术。 自成立以来，它已经注入了500个基因和40个ES细胞克隆，包括 “击倒”和“敲入”模型。超过3,500只创始动物 提供了过去两年，该设施提供了248个工作日， 每年与来自五个项目的23名不同资助的癌症中心成员 地区收入的增加和来源使收入的减少成为可能。 向调查员收取的费用从1999年每个项目1 500美元增加到750美元。进一步 预计利用率的扩大是基于 遗传学设施和教职员工。

Description: (Applicant's Description) The Transgenic Animal/Embryonic Stem Cell Shared Facility was initiated in 1991 and became a Cancer Center shared facility in 1995. Its purpose is to provide Cancer Center investigators with Pathogen-Free transgenic mice with high standards of quality control and efficiency. The service also provides advice and consultation to first time users, rederivation of stocks, cryopreservation and associated technologies. Since inception, it has injected 500 genes and 40 ES cell clones including "knockout" and "knock in" models. Over 3,500 founder animals have been provided. Over the past two years, the facility has provided 248 effort days per year with 23 different funded Cancer Center members from five program areas. Increasing volume and sources of revenue has allowed a reduction in charges to investigators from $1,500/project to $750/project in 1999. Further expansion of utilization is projected based on institutional expansion of genetics facilities and faculty members.