Graphene based electronic sensors for gas and VOC detection

该项目将开发集成的“生物芯片”传感器，采用半导体工艺，结合化学和生化表面改性。该设备将基于石墨烯平台，并结合微流体，能够检测超低浓度的生物标志物。这种传感器将能够检测血液、尿液甚至呼吸中的生物标志物。该生物传感器由附着在石墨烯表面的受体分子或实体（抗体、适体等）组成，能够选择性地与特定目标生物标志物相互作用。带电生物标记物和生物受体之间的结合事件会产生石墨烯纳米通道表面电荷密度的变化，这可以通过传感器设备的电行为变化来检测（本质上，纳米通道的耗尽导致通道电阻的变化）。研究工程师将致力于开发一种基于石墨烯的“电子鼻”传感器。在这个阶段，该设备的细节在商业上是受限的。这项研究将在斯旺西大学纳米健康中心（CNH）进行。

This project will develop integrated "Bio-chip" sensors, using semiconductor processes, combined with chemical and biochemical surface modification. Devices will be based on a graphene platform and combined with micro-fluidics to enable detection of biomarkers at ultra-low concentrations.The sensor will be capable of detecting biomarkers in blood, urine or even breath. The biosensor consists of a receptor molecule or entity (antibody, aptamer etc.) attached to the graphene surface, which is capable of interacting selectively with a specific target biomarker. This binding event between the charged biomarker and the bioreceptor produces a change in the charge density at the graphene nanochannel surface, that can be detected as a change in the electrical behaviour of the sensor device (essentially, a depletion of the nanochannel resulting in a change in the channel resistance).The Research Engineer will look to develop a graphene based "electronic nose" sensor. Details of the device are commercially restricted at this stage. The research will be undertaken at the Centre for Nanohealth (CNH) at Swansea University.