SCORE PROGRAM AT NEW MEXICO STATE UNIVERSITY, LAS CRUCES

这是拉斯克鲁塞斯新墨西哥州立大学（NMSU）新SCORE项目的申请。新密西根州立大学的一个目标是扩大该机构的研究，以便希望从事生物医学科学学科的少数民族学生参与。拟议的SCORE计划有其目标：(i)通过增加从事生物医学研究的教师数量，增加专门的单用户研究仪器的库存，提高研究仪器的维护能力，显著提高新密歇根州立大学开展生物医学相关研究的能力；（ii）通过扩大教师参与的资助努力和提高研究出版物的数量和质量，显著提高新国立大学生物医学研究的数量和质量；（三）将SCORE计划的活动与预期的RISE计划结合起来，通过让学生参与SCORE计划的研究项目，最大限度地利用资源培训生物医学科学领域的少数民族科学家；（iv）通过让训练有素的人员参与SCORE项目的评估计划，并使项目接受外部评估委员会的年度审查，提高新密歇根州立大学自我评估、评估和监督其多组成部分研究项目的能力。此申请包含19个研究子项目和3个试点子项目的研究建议。这些学科包括农学、动物科学、人类学、生物化学、生物学、化学、化学工程、分子生物学、微生物学和心理学。拟参与项目的研究课题包括：用锝和铼对医学诊断试剂进行放射性标记的方法、鸟类心血管适应性、细菌蛋白体、CHO细胞的糖基化过程、细胞凋亡、大肠杆菌O157:h7的耐酸性、二次代谢代谢工程、RNA病毒进化、胞质和叶绿体谷氨酰胺合成酶、生物脱氯反应、环境应激抵抗机制、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应、生物脱氯反应和生物脱氯反应。swainainine的毒代动力学，生长激素的神经调节，母婴皮质醇和行为发育的同步，胚胎血压的控制，粘土的修饰以解决外消旋混合物，内耳发育过程中的基因表达，阳离子螯合剂的化学合成，类固醇和etopo苷衍生物，以及硼化生物分子。自1974年以来，已有280名少数民族学生（占参与者的83%）进入学士学位课程，并培养了52名少数民族博士学位获得者，该计划将延续已有24年历史的MBRS计划。

This is an application for a new SCORE Program at New Mexico State University (NMSU) at Las Cruces. A goal of NMSU is to expand research is at the institution for participation by ethnic minority students who desire to pursue careers in the biomedical science disciplines. The proposed SCORE Program has its goals: (i) To significantly improve the capabilities of NMSU to conduct biomedically relevant research by increasing the numbers of faculty who conduct biomedical research, increasing the inventory of specialized single-user research instrumentation, and improving the capacity to maintain research instrumentation; (ii) To significantly improve the quantity and quality of biomedical research conducted at NMSU by broadening grantsmanship efforts of faculty participants and increasing the numbers and quality of research publications; (iii) To integrate the activities of the SCORE Program with an anticipated RISE Program to maximize resources for training minority scientists in the biomedical sciences by engaging students in SCORE Program research projects; (iv) To increase the capacity of NMSU to self-evaluate, assess, and monitor its multi- component research programs by engaging trained personnel in the SCORE Program's evaluation plan and subjecting the Program to annual review by an external evaluation committee. This application contains research proposals for nineteen research subprojects and three pilot subprojects. Disciplines represented among these proposals include Agronomy, Animal Science, Anthropology, Biochemistry, Biology, Chemistry, Chemical Engineering, Molecular Biology, Microbiology and Psychology. The research topics of proposed projects include methods for radiolabeling medical diagnostic reagents with technetium and rhenium, avian cardiovascular adaptations, the bacterial proteosome, glycosylation processes in CHO cells, apoptosis, acid tolerance of E. coli O157:h7, metabolic engineering of secondary metabolism, evolution of RNA viruses, cytosolic and chloroplastic glutamine synthase, biological dechlorination reactions, mechanisms of environmental stress resistance, toxicokinetics of swainonine, neuromodulation of growth hormone, maternal/infant synchrony in cortisol and behavior development, embryonic control of blood pressure, modification of clays for resolving racemic mixtures, gene expressions during inner ear development, and chemical synthesis of cation chelators, steroids and etoposide derivatives, and boronated biomolecules. This SCORE Program will continue a 24-year old MBRS Program which has advanced 280 minority students (83% of participants) on to post baccalaureate programs and produced 52 minority Ph.D. recipients since 1974.