AIAN Cohort Physical Activity Questionaire Validation

描述（由申请人提供）： 美国印第安人和阿拉斯加原住民（AIAN）社区和部落之间的慢性病发病率差异很大，原因基本上是未知的。大多数部落的慢性病发病率和死亡率的趋势没有得到很好的记录，但似乎很清楚的是，过去20年来，糖尿病和心脏病的发病率和死亡率一直在上升，印第安人和土著民族的癌症发病率相差五倍。虽然发病率的一些变化可能有遗传基础，但饮食摄入量，身体活动模式和其他生活方式特征的变化可能会导致这些差异。在AIAN中很少进行慢性疾病病因学的研究。特别缺乏的是队列研究。虽然在过去的25年中已经建立了许多队列，但AIAN人群仍然是美国的单一种族人群，尚未被纳入正在进行的国家营养监测系统或大型队列研究。 美国阿拉斯加印第安人队列研究（简称EARTH或健康教育和研究）的主要科学目标是确定饮食，体育活动和其他生活方式和文化因素与慢性疾病（如癌症，心血管疾病，中风，糖尿病，慢性肺部和呼吸系统疾病）的发展和进展以及死亡时的年龄。我们将研究为什么有些人保持健康，而其他人发展这些疾病。迄今为止，这是关于饮食和生活方式对美洲印第安人和阿拉斯加原住民疾病影响的最大和最全面的研究。为了了解身体活动与健康和疾病之间的关系，有必要对身体活动进行有效和可靠的测量。本提案的主要目的是验证这一人群的体力活动调查表。有效工具的可用性可能会增强未来的生活方式监测工作。

DESCRIPTION (provided by applicant): Rates of chronic diseases vary substantially among American Indian and Alaska Natives (AIAN) communities and tribes for reasons that are largely unknown. Trends in chronic disease incidence and mortality are not well-documented for most tribes, but it does seem clear that diabetes and heart disease incidence and mortality have been increasing over the past two decades and that there is a fivefold variation in incidence rates of cancer among AIAN. While some of the variation in disease rates may have a genetic basis, most likely variations in dietary intake, physical activity patterns, and other lifestyle characteristics contribute to these differences. Few studies of the etiology of chronic diseases have been done in AIAN. Particularly lacking are cohort studies. While numerous cohorts have been established in the last 25 years, the AIAN populations remain the single ethnic population in the United States that has not been included in either the ongoing National Nutrition Monitoring System or large cohort studies. The major scientific goal of the American Indian Alaska Native cohort study, (referred to as EARTH or Education And Research Towards Health) is to determine how diet, physical activity, and other lifestyle and cultural factors relate to the development and progression of chronic diseases such as cancer, cardiovascular diseases, stroke, diabetes, chronic lung and respiratory diseases, and age at time of death. We will examine why some people remain healthy when others develop these diseases. To date, this is the largest and most comprehensive study of diet and lifestyle influences on disease among American Indians and Alaska Natives. In order to understand the nature of the relationship of physical activity to health and disease a valid and reliable measure of physical activity is necessary. Validation of the physical activity questionnaire for this population is the main objective of this proposal. The availability of a valid instrument could potentially enhance future lifestyle surveillance efforts.