Emotion Regulation in Suicidal Patients with BPD

辩证行为疗法（DBT）是一种认知行为疗法，专门用于治疗边缘型人格障碍（BPD）的自杀个体。迄今为止，已经完成了8项随机试验和4项对照试验，证明了DBT的有效性。大量试验正在进行或计划进行。然而，很少有实证研究对治疗所依据的Linehan的BPD基础理论进行了检验。没有研究检验Linehan的主要假设，即情绪调节的改善与临床结果的改善有关。本研究的目的是：1)开发和评估适合未来纵向治疗使用的情绪调节和失调的创新多方法实验室和现场测量方法；3)通过比较自杀性BPD患者和健康对照者对测量电池的反应来检验Linehan理论提出的假设。我们将在三个时间点对情绪脆弱性和调节进行五项原则测试：1)无压力任务期间的基线情绪测量，2)情绪唤起电影，3)问题解决任务与挫折容忍和延迟满足任务配对，以及4)压力任务后的信息处理任务和5)32小时动态监测。

Dialectical Behavioral Therapy (DBT) is a cognitive-behavioral treatment developed specifically for the treatment of suicidal individuals meeting criteria for Borderline Personality Disorder (BPD). Eight randomized trials and four controlled trials have been completed to date demonstrating the efficacy of DBT. A large number of trials are underway or planned. However, very few empirical studies have been conducted testing the Linehan's underlying theory of BPD on which the treatment is based. No studies have examined Linehan's principle hypothesis that improvements in emotion regulation are associated with improved clinical outcomes. Aims of this research are to: 1) develop and evaluate innovative multi-method laboratory and field measures of emotion regulation and dysregulation suitable for use in future longitudinal treatment and 3) test hypotheses generated by Linehan's theory by comparing responses on the measurement battery of suicidal BPD patients with healthy controls. We intend to examine five principle tests of emotional vulnerability and regulation given at three time points: 1) baseline emotion measures during a non-stressful task, 2) emotionally evocative films, 3) a problem-solving task paired with tasks of frustration tolerance and delay of gratification, and 4) an information processing task following a stressful task and 5) 32-hour ambulatory monitoring.