Conference Proposal: Calcium and Cell Function

描述（由申请人提供）：申请资金用于在科罗拉多州斯诺马斯举行的2004年FASEB钙和细胞功能会议的部分支持。钙是关键的第二信使，在T细胞发育、生育、神经递质释放、感觉传导和细胞迁移等过程中都是必不可少的。此外，钙信号的缺陷与一系列影响可兴奋细胞和不可兴奋细胞的疾病有关。该会议每两年举行一次，旨在为来自不同领域的科学家提供一个论坛，展示和讨论钙领域最新和最令人兴奋的发展。我们的目标是吸引许多没有参加过以前钙信号会议的科学家参加这次会议，尽管他们的工作与这次会议的主题相关。特别是，许多研究感觉信号、神经元发育和神经元生理学的科学家没有参加过去的会议，因为以前的重点是不可兴奋的细胞。我们期望参与者的组合，加上非正式的环境和相对适度的会议规模（最多165名参与者），能够在通常不参加相同会议的科学家之间产生热烈的讨论和建立新的互动。会议将包括九个会议，包括口头报告、两个主题演讲和四个海报会议，主题包括钙对基因表达的调节、感觉信号、钙对发育的调节以及钙对囊泡和蛋白质运输的调节。会议将讨论的主题具有根本性的重要性，并与了解诸如神经退行性疾病、交流障碍、衰老、癌症、肾脏和心血管疾病等疾病的基础有关。

DESCRIPTION (provided by applicant): Funds are requested to cover partial support for the 2004 FASEB Conference on Calcium and Cell Function, to be held in Snowmass, Colorado. Calcium is a critical second messenger, which is essential for processes ranging from T cell development to fertility, neurotransmitter release, sensory transduction and cell migration. Furthermore, defects in calcium signaling are associated with a host of diseases affecting excitable and non-excitable cells. The goal of this conference, which takes place every two years, is to provide a forum for scientists from a diversity of fields to present and discuss the latest and most exciting developments in the calcium field. We have aimed to attract many scientists to this meeting who have not participated in previous conferences on calcium signaling, despite the relevance of there work to the topic of the meeting. In particular, many scientists who work on sensory signaling, neuronal development and neuronal physiology have not attended past meetings, due to a former emphasis on non-excitable cells. We expect the mix of participants, combined with the informal setting and relatively modest size of the meeting (maximum of 165 participants), to generate lively discussions and the establishment of new interactions among scientists who ordinarily do not attend the same conferences. The meeting will include nine sessions with oral presentations, two keynote addresses and four poster sessions covering topics ranging from calcium regulation of gene expression to sensory signaling, calcium regulation of development and regulation of vesicular and protein trafficking by calcium. The topics to be covered at the meeting are of fundamental importance and are relevant to understanding the bases of a diseases such as neurodegeneration, communicative disorders, aging, cancer, kidney and cardiovascular disease.