2004 Reproductive Tract Biology Gordon Conference

描述（由申请人提供）：本申请为2004年6月6日至11日举行的生殖道生物学戈登会议申请部分资金。请注意，由于会议的科学内容，我们要求国家儿童健康与人类发展研究所作为会议的主要赞助商。我们还要求妇女健康办公室、国家癌症研究所、国家糖尿病、消化和肾脏疾病研究所、国家环境健康科学研究所、国家人类基因组研究所和国家普通医学科学研究所联合赞助。邀请的赞助者数量反映了本次会议的不同寻常的性质，它侧重于生物学，以及男性和女性生殖道的器官和器官系统的病理学，而不是特定的分子或过程和乳腺癌。因此，这次会议吸引了从基础科学到临床实践的各种领域和背景的参与者。因此，本次会议的主要目标是促进有关生殖道和与乳腺正常和病理过程相关的机制的跨学科交流和信息整合。三个具体目标将使我们能够实现这一目标：第一，会议的科学内容将达到最高水平。为了达到这一卓越标准，我们邀请国际公认的专家在各自领域的前沿发言。这是一个有趣的组合，既有多年来在各自领域处于领先地位的知名研究人员，也有其他领域同样知名的研究人员，他们对转基因小鼠的表型分析揭示了这些分子在生殖道中的意想不到的新作用。此外，还将重点介绍克隆对胚胎发育影响的前沿科学以及基因组学和蛋白质组学在生殖生物学中的应用。其次，强调与重要临床问题高度相关的研究，并有可能转化为医疗实践。例如，一整个会议的重点是乳腺激素信号传导机制，特别强调导致乳腺癌的异常，另一个会议则是影响生殖结果的临床表现。第三，非常强调学生和年轻同事的参与，因为任何领域的未来都取决于下一代研究者。总之，我们计划了一个令人兴奋的会议，它符合生殖系统生物学戈登会议的丰富传统，该会议已经存在了34年。在同一地点继续与哺乳动物配子发生和胚胎发生会议会面将进一步提高会议的质量，与会者一直高度评价这次会议。

DESCRIPTION (provided by applicant): This application requests partial funding for the Reproductive Tract Biology Gordon Conference to be held June 6-11, 2004. Please note that due to the scientific content of the meeting we request the National Institute of Child Health and Human Development as the primary sponsor of the meeting. We also request joint sponsorship by the Office of Women's Health, the National Cancer Institute, National Institute of Diabetes, Digestive and Kidney Diseases, the National Institute for Environmental Health Sciences, National Human Genome Research Institute and the National Institute of General Medical Sciences. The number of requested sponsors reflects the unusual nature of this conference, which focuses on the biology, and the pathology of the organs and organ systems of the male and female reproductive tracts, rather than on specific molecules or processes and on breast cancer. Therefore, this meeting attracts participants from a wide variety of fields and backgrounds ranging from basic science to clinical practice. Accordingly, the principal goal of this conference is to stimulate cross-disciplinary exchange and integration of information concerning the reproductive tract and mechanisms associated with normal and pathological processes in the mammary gland. Three specific aims will allow us to accomplish this goal: First, the scientific content of the meeting will be at the highest level. To achieve this standard of excellence, we are inviting speakers who are internationally recognized experts at the forefront of their fields. There is an interesting blend of established investigators who have been leaders in their respective areas for many years and equally renowned researchers in other fields whose phenotypic analyses of transgenic mice have uncovered unexpected and novel actions of these molecules in the reproductive tract. In addition, cutting edge science on the effects of cloning on embryo development and the applications of genomics and proteonomics to reproductive biology will also be highlighted. Second, there is a strong emphasis on research that is highly relevant to important clinical questions and has potential for translation into medical practice. For example, one entire session focuses on mechanisms of hormonal signaling in the context of the mammary gland with a special emphasis on aberrations that lead to breast cancer and another on clinical manifestations that affect reproductive outcomes. Third, there is a strong emphasis on the inclusion of students and junior colleagues because the future of any field depends on the next generation of investigators. In summary, we have planned an exciting meeting that is in accord with the rich traditions of the Reproductive Tract Biology Gordon Conference, which has been in existence for 34 years. The continued ability to meet with the Mammalian Gametogenesis and Embryogenesis Conference at the same site will further enhance the quality of this meeting, which has consistently been highly rated by the attendees.