Genetic Manipulation of Insects

描述(申请人提供)：昆虫分子遗传学是生物学的一个广泛领域，在过去几年中取得了重大进展。其中一些关键进展包括完成了黑腹果蝇和冈比亚按蚊的基因组测序项目，启动了意大利蜜蜂和埃及伊蚊的基因组测序项目，继续开发昆虫生殖系转化技术，使一些非果蝇物种的转化现在成为例行公事，以及利用种系转化技术创造出难以发育疟原虫的转基因蚊子。这些发展导致昆虫分子基因发现的速度和复杂性大幅提高，证明有必要在这个时候召开一次会议，总结、综合和促进这一重要生物学领域的继续研究。与其他与昆虫有关的会议相比，这里描述的Keystone研讨会有一个独特的潜在主题，即昆虫的遗传操纵。因此，本次会议将把许多最先进的昆虫分子遗传科学和技术与促进昆虫遗传操作的兴趣结合起来，作为基本实验室研究的一部分，并作为解决当今人类面临的一些与昆虫有关的最重要问题的工具。这是唯一一次有这样一个基本主题的与昆虫有关的会议，其中包括广泛的昆虫学系统。这也是一次非常成功的会议，吸引了研究黑腹果蝇的顶尖研究人员，导致了最高水平的无与伦比的多学科互动。这次会议对于研究生和博士后研究员来说是一个难得的机会，他们可以获得昆虫分子遗传学领域的高水平概要，并进行重要的职业发展互动。

DESCRIPTION (provided by applicant): Insect molecular genetics is an extensive field of biology that has experienced major advances within the last few years. Some of those key developments include the completion of genome sequencing projects for Drosophila melanogaster and Anopheles gambiae, the initiation of genome sequencing projects for Apis mellifera and Aedes aegypti, the continued development of insect germ-line transformation technology such that for a number of non-drosophilid species transformation is now routine, and the use of germ-line transformation technology to create transgenic mosquitoes refractory to Plasmodium development. These developments are resulting in a substantial increase in the pace and sophistication of insect molecular genetic discoveries, justifying the need to convene a conference at this time that summarizes, synthesizes and promotes continued research in this important area of biology. This Keystone Symposium described here has a unique underlying theme relative to other insect-related conferences, namely the genetic manipulation of insects. Consequently this meeting will integrate much of the most advanced insect molecular genetic science and technology with an interest in promoting the genetic manipulation of insects as part of basic laboratory studies and as a tool for combating some of the most important insect related problems facing humanity today. It is the only insect-related conference with such an underlying theme that includes a broad scope of entomological systems. It is also a meeting that has been distinctively successful in attracting the top researchers working with Drosophila melanogaster, resulting in matchless multidisciplinary interactions of the highest caliber. The meeting is an uncommon opportunity for graduate students and postdoctoral fellows to obtain a high level synopsis of the field of insect molecular genetics and to make important career-advancing interactions.