Vaginal Microbicide Acceptability STD/HIV Prevention

超出提供的空间。这是一份修改后的申请表。这项拟议研究的主要目标是探索与阴道杀菌剂可接受性相关的因素。样本将从青春期中后期的高危女性中提取。研究分为两个阶段。第一阶段将包括焦点小组、个人访谈和性二重人格访谈，以确定感兴趣的相关方面，并发展对文化影响和适当语言的理解。第二阶段将包括对各种维度(在第一阶段制定)对阴道杀菌剂用于预防性病的可接受性的相对重要性进行评估。从市场研究的角度出发，选择概念测试作为评估某一特定杀菌剂试用的可能性的最佳方法。可接受性被操作为尝试具有特定特征的假想杀微生物剂的意图。理论框架是从计划行为理论改编而来的。其他结构将从创新扩散理论中提取。将使用一系列视频片段来评估行为意图，以模拟性决策的真实场景，分析将侧重于与可接受性相关的产品特征、与接受相关的态度和与实际使用相关的社会规范，并基于初步可接受性估计进行预测。一个来自青少年医学、心理学和营销学的多学科团队被召集起来进行这项研究。这个团队在对青少年进行临床和营销研究方面经验丰富，这些研究主题涉及性行为、性传播疾病和接受与性病相关的疫苗。PERFORMANCESITE(========================================Section End===========================================

EXCEED THE SPACE PROVIDED. This is a revised application. The primary goal of the proposed research is to explore factors associated with vaginal microbicides acceptability. The sample will be drawn from high-risk women in middle and late adolescence. The research is organized into two phases. Phase 1will consist of focus groups, individual interviews and sexual dyad interviews in order to identify relevant dimensions of interest as well as develop understanding of cultural influences and appropriate language. Phase 2 will consist of an assessment of the relative importance of the ~arious dimensions (developed in Phase 1) on acceptability of vaginal microbicide use for STD prevention. Drawing from the perspective of marketing research, a concept test is chosen as the best methodology to assess Lhe likelihood of a trial of use of a given microbicide. Acceptability is operationalized as intention to try a hypothetical microbicide with specified characteristics. The theoretical framework is adapted from the Theory ot Planned Behavior. Additional constructs will be drawn from Diffusion of Innovation Theory. Behavioral intention will be assessed using a series ofvideo vignettes in orderto simulate real-life scenarios of sexual decision-making Analyses will focus on product characteristics associatedwith acceptability, attitudes and social norms associated with acceptance and forecasting of actual use based on initial acceptability estimates. A multi-disciplinary team drawn from adolescent medicine, psychology and marketing is assembled to conduct the research. This team is substantially experienced in conducting clinical and marketing research with adolescents addressing topics of sexual behavior, sexually transmitted diseases and acceptance of STD-related vaccines. PERFORMANCESITE( ========================================Section End===========================================