Intergenerational Transmission of Antisocial Behavior

描述(由申请人提供)：虽然众所周知，反社会 行为在家庭中存在，令人惊讶的是，人们对具体的行为知之甚少 疾病从一代传到下一代的机制。而当 代际传播范式正变得越来越 在解决这一问题方面具有影响力，但很少有这样的研究是前瞻性的， 包括父母双方，注重早期机制，以及解决女性和 男性的反社会行为。重要的是，到目前为止还没有人检查过生物学 对代际延续和变化的影响，或它们如何相互作用 与社会因素一起调节反社会行为的传播。 拟议的三代研究试图解决这些知识差距 通过利用一种新的设计，对795名男性和女性进行了测试 关于年龄的心理生理、行为、营养和认知测量 3，而他们的第一代父母则接受心理社会评估 影响。这些第二代三岁的孩子现在30岁， 将与他们的第三代三岁孩子一起重新测试 后代，在心理生理，心理社会，认知，行为上， 养育子女和反社会行为措施。都是第二代亲本 他们之前未接受过测试的配偶将接受心理生理测试 衡量标准，以及生活压力、日常烦恼、家庭状况的衡量标准 冲突、精神疾病和犯罪行为。这项研究还将评估 是否对3-5岁的儿童进行营养、锻炼和教育 在100名第二代受试者中，这导致了 11岁时生理唤醒和注意力集中，行为减少 17岁时出现精神障碍，扰乱疾病的代际传播 从第二代到第三代的反社会行为。 人们认为，这项研究提供了一个真正独特的机会来理解 生物影响如何与社会背景相互作用这一未被探索的问题 在阻止或促进代际传播中 反社会和攻击性行为。这种新的知识，如果进一步发展， 可以为新一代更有效的预防计划做出贡献 减少反社会和暴力行为。

DESCRIPTION (provided by applicant): While it is well-known that antisocial behavior runs in families, surprisingly little is known about the specific mechanisms by which it is transmitted from one generation to the next. While the intergenerational transmission paradigm is becoming increasingly influential in addressing this issue, very few such studies are prospective, include both parents, focus on early mechanisms, and address female as well as male antisocial behavior. Importantly, none to date have examined biological influences on transgenerational continuity and change, or how they interact with social factors in modulating the transmission of antisocial behavior. The proposed three-generation study attempts to address these gaps in knowledge by capitalizing on a novel design in which I ,795 males and females were tested on psychophysiological, behavioral, nutritional, and cognitive measures at age 3, while their first-generation parents were assessed on psychosocial influences. These second-generation three-year-olds are now aged 30 years and will be retested, together with their third-generation three-year-old offspring, on psychophysiological, psychosocial, cognitive, behavioral, parenting, and antisocial behavior measures. Both the second generation parent and their previously untested spouse will be tested on psychophysiological measures, together with measures of life stress, daily hassles, family conflict, mental illness, and criminal behavior. The study will also assess whether a nutritional, exercise, and educational enrichment from ages 3-5 years in 100 of the second generation subjects, which has lead to increased physiological arousal and attention at age 11 years and reduced conduct disorder at age 17 years, disrupts the intergenerational transmission of antisocial behavior from the second to third generations. It is thought that the study offers a truly unique opportunity to understand the unexplored issue of how biological influences interact with social contexts in either blocking or facilitating the intergenerational transmission of antisocial and aggressive behavior. This new knowledge, if further developed, could contribute to a new generation of more effective prevention programs for reducing antisocial and violent behavior.