UCLA Mentored Clinical Pharmacology Research Scholar Pr*

描述(由申请人提供)： 这是一项在以患者为导向的研究中实施严格和高度结构化的指导临床学者计划的建议，该研究是广泛的、跨学科的，专注于临床药理学和实验治疗学领域。这一关键领域架起了分子医学和医疗保健的桥梁，涵盖了临床医学的所有领域。突出抓好妇女儿童、少数民族等特殊人群的研究。同样，我们将强调招募、保留和培训代表不足群体成员的学者。这份申请是由排名前十的加州大学洛杉矶分校和德鲁大学联合提交的，德鲁大学是历史上四所黑人医学院之一，也是密西西比河以西唯一的一所。这两个机构有着卓有成效的合作历史。这两个机构的综合临床研究中心(GCRC)将是该计划的关键资源。我们拥有一大批优秀的首席导师。学者们还将与我们的数据协调中心和数据管理安全中心密切合作。私家侦探胡里奥·利奇尼奥博士是一位成就卓著的西语裔以病人为中心的调查员。这个有指导的学者计划将由一个咨询委员会指导，该委员会包括非常有成就的面向患者的调查人员、学术领袖和一位基础科学家、诺贝尔奖获得者路易斯·伊格纳罗博士。我们还任命了一个外部咨询委员会，成员包括学术医学和科学传播方面的专家。除了我们对少数民族和特殊人群的研究和培训外，我们还有一个高度创新和全面的科学传播教学计划。我们将使用现有的结构，如加州大学洛杉矶分校的翻译研究研究生培训计划(K30)和临床研究的硕士计划，并将开发本申请中描述的新型教学组件。每名学者除其首席导师外，还将有一名具有临床研究设计和统计专业知识的联合首席导师，以及一名不直接参与其项目的研究导师，以提供额外的导师。学者们将与咨询委员会密切合作。加州大学洛杉矶分校为该项目提供了大量的机构、学术和资金支持。我们的目标是迅速成为这一领域领先的导师学者项目，并成为以患者为导向的、专注于特殊人群(包括少数民族)的调查的全国性资源。加州大学洛杉矶分校医学院教育发展和研究中心的教育工作者将实施机制来评估该计划的质量和结果，以实现持续改进的目的。

DESCRIPTION (Provided by the applicant): This is a proposal to implement a rigorous and highly structured mentored clinical scholar program in patient-oriented research that is broad, cross disciplinary and focused on the area of clinical pharmacology and experimental therapeutics. This key field bridges molecular medicine and health care and covers all areas of clinical medicine. We will place a strong emphasis on the conduction of research in special populations such as women, children, and members of ethnic minority groups. We will likewise emphasize the recruitment, retention, and training of scholars who are members of under represented groups. This application is being jointly submitted by UCLA, a top 10 university, and by Drew University, one of four historically Black medical colleges, and the only one west of the Mississippi. These two institutions have a history of highly productive collaborations. The General Clinical Research Centers (GCRCs) from both institutions will be key resources for the program. We have a large and superbly qualified pool of identified lead mentors. Scholars will also work closely with our Data Coordinating Center and Data Management Safety Centers. The P.I., Dr. Julio Licinio, is an accomplished Hispanic patient-oriented investigator. This mentored scholar program will be guided by an Advisory Committee that includes highly accomplished patient orient investigators, academic leaders, and one basic scientist, Dr. Louis Ignarro, a Nobel Laureate. We have also appointed an External Advisory Board that includes experts in academic medicine and communication of science. In addition to our research and training emphasis on minorities and special populations, we have a highly innovative and comprehensive program of instruction on the communication of science. We will use existing structures, such as the UCLA Graduate Training Program in Translational Investigation (K30) and the Master's Program in Clinical Research, and will also develop novel didactic components that are described in this application. Each scholar will have, in addition to her/his lead mentor, a co-lead mentor with expertise in clinical research design and statistics, and a research preceptor who is not directly involved in their project to provide additional mentorship. Scholars will work closely with the Advisory Committee. UCLA has provided substantial institutional academic and financial support to this program. Our goal is to rapidly become the leading mentored scholar program in this area and to become a national resource for patient-oriented investigation that is focused on special populations, including ethnic minorities. Educators from the UCLA Center for Educational Development and Research in the School of Medicine will implement mechanisms to evaluate the quality and outcomes of the program for purposes of continuous improvement.