Child Health Research Career Development Award

描述（由申请人提供）：本申请寻求持续支持 爱荷华州大学儿童健康研究职业发展项目。 目的是支持儿科医生的研究职业发展， 最近完成了专科 训练 建议继续 该计划为实验室和行政部门提供核心支持， 适用于若干国家的资源 研究项目， 发展生物学。 其中包括识别和定位 人类基因组中的基因，特定基因调节人类基因组的机制， 基因产物的合成，以及基因打靶和基因转移以研究基因 在组织发育中起作用。 首席研究员，项目主任， 并建立了研究人员，其资助的研究与 CHRCDA的重点将作为一个咨询委员会，从高度选择 合格的新教师儿科医生科学家新项目的三个收件人 发展资金始终。 每个学者都会进行调查 在一名或多名已确定的调查人员的指导下。 双方都将 在共享核心实验室进行分子生物学程序， 部分由大学配套资金支持，并由 核心实验室主任。 该奖项支持的学者也可以花费 在各自实验室工作的其他时间 成立调查员。 这项安排旨在提供具成本效益， 质量控制的仪器和程序性能的学者。 学者将参加讲座，研讨会和正式的研究生课程， 研究伦理，以及分子生物学技术和战略， 发育生物学 吸引妇女和少数民族儿科医生的措施 研究职业的人都被纳入了。 该计划预计将 利用跨学科研究的机构基础设施 并将建立在研究职业发展的部门传统。 它将促进生产力和协作，并加快 从基础科学的新发现到临床护理。

DESCRIPTION (provided by applicant): This application seeks ongoing support for the University of Iowa Child Health Research Career Development program. The purpose is to support the research career development of pediatricians who have recently completed subspecialty training. The proposal is to continue a program that provides core support for laboratories and administrative resources applicable to a number of research projects that address the molecular biology of development. These include the identification and localization of genes in the human genome, mechanisms by which specific genes regulate the synthesis of gene products, and gene targeting and gene transfer to study gene function in developing tissues. The Principal Investigator, Program Director, and established investigators whose funded research is closely related to the focus of the CHRCDA will act as an advisory committee to select from highly qualified new faculty pediatrician scientists three recipients of New Project Development Funds at all times. Each of the Scholars will conduct investigations under guidance of one or more identified established investigators. Each will perform molecular biologic procedures in a Shared Core Laboratory that is supported in part by university matching funds and is under the supervision of a Core Laboratory Director. Scholars supported by the award also may spend other periods of time working in the laboratories of their respective established investigators. This arrangement aims to provide cost-effective, quality-controlled instrumentation and procedure performance to Scholars. Scholars will attend lectures, seminars and formal graduate courses on research ethics, as well as on molecular biology techniques and strategies in developmental biology. Measures to attract women and minority pediatricians to research careers have been incorporated. The program is anticipated to capitalize on an institutional infrastructure of interdisciplinary research and will build upon a departmental tradition of research career development. It will promote productivity and collaboration and speed the application of new basic science discoveries to clinical to clinical care.