Metal-organic cages for chemical separations

该项目将整合Nitschke集团（化学）和Torrente集团（化学工程和生物技术）的专业知识，以开发该项目将利用Nitschke集团的现有专业知识，开发一种从原油，生物原料和天然产物混合物中分离有用构件的新方法。一旦被封装，客体就与其外部环境隔离，并在主体纳米胶囊的受激相转移期间充当分子货物。最近，我们已经开发出使用阴离子作为刺激来驱动这种相转移。这些刺激是有效的，但导致盐副产物在系统中的积累。本项目将建立在我们最近的进展，通过开发新的“干净”的刺激，以触发相转移的笼，并通过创建功能的客人分离系统。

This project will integrate expertise in the Nitschke group (Chemistry) and Torrente groups (Chemical Engineering and Biotechnology) to develop This project will utilise the prior expertise of the Nitschke group to develop a new means of separation of useful building blocks from crude oil, bio-feedstocks, and natural product mixtures. Once encapsulated, the guests are isolated from their external surroundings and act as molecular cargoes during the stimulated phase transfer of the host nano-capsules. Very recently, we have developed the use of anions as stimuli to drive this phase transfer. These stimuli are effective but result in the accumulation of salt by-products in the system. The present project would build upon our recent progress by developing new 'clean' stimuli to trigger phase transfer of cages and by creating functional guest separation systems.