Novel Organic Cages as Moduli for Extended Three-dimensional Networks

罗格斯大学化学系Elena Galoppini教授， 纽瓦克是由有机和大分子计划的支持， 化学部根据研究规划补助金建立一个 合成方法导致新的有机笼状分子。 由市售金刚烷制备的衍生物， 偶联四苯基甲烷以获得坚固的刚性笼， 直径在18埃到28埃之间的内腔。 Galoppini教授提出了一种巧妙的方法来合成 有机笼状结构，具有所需的刚性， 用于合成扩展的、多孔的、超分子有机物的模量 网络. 研究规划补助金在这个阶段的教授 Galoppini的职业生涯提供了一种利用化学的手段， 在一个非常有竞争力的环境中，NSF研究提案所需的方法 区 可剪裁结构的多孔有机材料是一种有吸引力的 补充目前可用的多孔无机材料。 的 然而，这种材料的合成依赖于以下构件： 具有足够的刚性以支撑所述多个元件的延伸的三维阵列， 个别单位。 使用市售可得的 将开发试剂以提供一系列刚性有机笼， 将作为构建模块。三维材料将是 组装有可定制的孔隙，以允许扩散， 封装不同的试剂。

Professor Elena Galoppini, Department of Chemistry, Rutgers University at Newark is supported by the Organic and Macromolecular Program of the Chemistry Division under a Research Planning Grant to establish a synthetic methodology leading to novel organic cage molecules. Derivatives prepared from commercially available adamantanes and tetraphenylmethanes are coupled to achieve robust, rigid cages with internal cavities ranging from 18 to 28 angstroms in diameter. Professor Galoppini presents a clever approach to the synthesis of organic cage structures that possess the rigidity needed to serve as moduli for the synthesis of extended, porous, supramolecular organic networks. A Research Planning Grant at this stage in Professor Galoppini's career offers a means to exploit the chemistry, and develop the methodology needed for an NSF research proposal in a very competitive area. Porous organic materials of tailorable architecture are an attractive complement to currently available porous, inorganic materials. The synthesis of such materials, however, rests on building blocks of sufficient rigidity to support an extended three dimensional array of the individual units. A synthetic methodology using commercially available reagents will be developed to afford a series of rigid organic cages that will serve as building blocks. Three dimensional materials will be assembled with tailorable porosities to allow the diffusion and encapsulation of different reagents.