The Synthesis and Development of New Imaging Agents of the Translocator Protein

博士项目将开发新的有机合成化学，用于快速有效地制备化学显像剂，可用于研究与转运蛋白相关的一系列神经系统疾病。特别是，我们将研究新的过渡金属催化转化与一锅多键形成反应工艺相结合，以制备高功能的类药物杂环支架。这些过程将用于制备可用于PET和SPECT成像的分子示踪剂

The PhD project will develop new organic synthetic chemistry for the rapid and efficient preparation of chemical imaging agents that can be used to study a range of neurological diseases associated with the translocator protein. In particular, we will investigate new transition metal catalysed transformations in combination with one-pot multi-bond forming reaction processes for the preparation of highly functional, drug-like heterocyclic scaffolds. These processes will be used to prepare molecular tracers that can be used in PET and SPECT imaging