Training in Investigative and Molecular Dermatology

描述（由申请人提供）：本申请是一个竞争性的 更新调查和分子皮肤病学培训计划， 成立于1991年，隶属于凯斯西院皮肤科 储备大学（CWRU）和克利夫兰大学医院（UHC）。这 该计划得到了CWRU，UHC和UHC研究部门的全力支持， 大学医院研究所（UHRI），以UHRI和 如果获得资金，妇女地位和资源股将为这一培训方案提供机构支助。主要 该计划的目标是继续培养高素质的年轻人， 研究人员的职业生涯在生物医学研究相关的皮肤。这是 通过为最先进的跨学科提供机会来实现 研究性皮肤病学和皮肤生物学的研究培训。资格 候选人将是那些持有医学博士/或医学博士/博士或者博士学位 多年的博士后经验，无论是与一个明确的承诺， 研究性皮肤病学或基础皮肤生物学的学术生涯。 个性化的职业生涯建设计划是为学员在其中一个开发 四个专题研究领域，每个领域都与 皮肤生理学和病理学：免疫生物学和实验 免疫病理学、细胞和分子生物学、光医学和 转化研究和皮肤药理学/致癌作用。每个同胞 选择这四个训练轨道中的一个，每个训练轨道都由 主任和联合主任和参与教师。因此，每个学员 获得他/她的顾问，共同导师和一个重点小组的培训， 专家每个主要顾问都有一个由联邦政府资助的调查员， 发起了一个同行评审的项目，他们是PI。那些落下的短裤 这一标准，但积极和独立的研究计划，作为 共同顾问。通过这一重点突出但互动的机制，学员们 提供了建立假设的指导， 皮肤生物学中的问题，在设计和性能的连贯设置 实验，并在获得经验与现代研究方法和 技术.此外，还提供正式的培训，使学员了解作为一名 科学家和数据分析，以公布结果。此外该 研究员参加课程、讲习班、专题讨论会和数据介绍 并被要求在科学会议上介绍他们的工作 包括CWRU/UHC皮肤病研究中心讲师和年度 皮肤病研究学会的会议。因此，培训发生 通过参与有针对性的研究项目并通过 会议/研讨会，其中基础科学研究，以及 积极促进研究成果在临床问题上的应用。这 基于CWRU和UHC/UHRI的多学科中心创建了一个基金会 基础科学和临床部门之间的合作互动， 为考虑从事以下职业的年轻调查人员提供培训环境： 学术皮肤病学。

DESCRIPTION (provided by applicant): This application is for a competitive renewal of the Training Program in Investigative and Molecular Dermatology that was established in 1991 in the Department of Dermatology at Case Western Reserve University (CWRU) and University Hospitals of Cleveland (UHC). This program has the full support of CWRU, UHC, and the research arm of UHC, Research Institute of University Hospitals (UHRI), as evidenced by UHRIs and CWRUs institutional support for this training program, if funded. The major objective of this program is to continue to prepare highly qualified young investigators for careers in biomedical research relevant to the skin. This is accomplished by providing opportunities for state of the art interdisciplinary research training in investigative dermatology and cutaneous biology. Eligible candidates will be those holding M.D./or M.D./Ph.D. or Ph.D.s with up to two years of postdoctoral experience, both with a definite commitment to an academic career in investigative dermatology or basic cutaneous biology. Individualized career building programs are developed for trainees in one of four research thematic research areas, each of which is related to the physiology and pathology of the skin: immunobiology and experimental immunopathology, cellular and molecular biology, photomedicine and translational research, and skin pharmacology/carcinogenesis. Each fellow selects one of these four training tracks, each of which is coordinated by the Director and Co Director and participating faculty members. Thus, each trainee obtains training by his/her advisor, a co mentor, and a focused group of experts. Each primary advisor has an active federally funded, investigator initiated peer reviewed program on which they are P.I. Those falling shorts of this criterion, but are active and independent in the research program serve as co advisors. Through this focused, yet interactive mechanism, the trainees are provided guidance in building hypotheses for scientifically approaching problems in cutaneous biology, in the design and performance of a coherent set of experiments, and in gaining experience with modem research methodology and technology. Formal training is also provided in the ethical conduct of being a scientist and analysis of data for publication of results. In addition, the fellows participate in courses, workshops, symposia and data presentation exercises and are required to present their work at scientific meetings including the CWRU/UHC Skin Diseases Research Center lectureship and the annual meeting of the Society for Investigative Dermatology. Thus, training occurs through participation in a focused research project and through conferences/seminars in which the basic science research, as well as the application of research to clinical problems are actively facilitated. This multidisciplinary Center based at CWRU and UHC/UHRI has created a foundation for cooperative interactions between basic science and clinical departments and provides a training milieu for young investigators contemplating a career in academic dermatology.