Immunology and Immunooncology Training Program

描述（由申请人提供）：这是免疫肿瘤学培训补助金的竞争性更新，已经存在了30多年。我们为希望成为免疫肿瘤学和免疫学领域独立研究人员的高级博士生和博士后提供高质量的培训。在现代生物学方面提供广泛的培训，特别强调遗传，分子，细胞生物学和结构方法来解决免疫肿瘤学和免疫学中的问题。该培训基金主要用于微生物学与免疫学、生物化学、细胞生物学、发育与分子生物学、妇科肿瘤学、核医学、妇产科、病理学和儿科等部门的22名教职员工的培训和研究。我们的研究和培训环境的一个重要组成部分是我们完善的AECOM癌症中心，由I. David Goldman博士领导。我们所有的教练都是会员。我们的博士预科课程在苏·戈尔丁研究生院的指导下运作。该项目包含了仔细招生过程的基本要素，以基础课程为核心，其次是免疫学专业课程，辅以研讨会、期刊俱乐部、正在进行的会议、外部演讲，以及对每个学生在博士前和博士后阶段的研究项目的密切监督。贝尔弗高级生物医学研究所的建立确保了博士后在研究经验和职业机会方面的特殊关注得到解决。我们的培训计划最重要的特点是博士生和博士后学员在实验室的密集工作，从到校开始，一直在严密的监督下进行。我们的项目还包括在共享设施中包含的相关仪器的培训，包括杂家瘤设施，FACS设施，转基因小鼠和干细胞设施，x射线晶体学和分子建模，肽合成和蛋白质测序，寡核苷酸合成和DNA测序以及微阵列设施。未来5年，我们将继续强调癌症相关研究，并将新的重点放在转化和临床研究上。

DESCRIPTION (provided by applicant): This is a competitive renewal of a training grant in immuno-oncology that has been in existence for over 30 years. With this vehicle we provide high quality training for advanced predoctoral and postdoctoral students who desire careers as independent investigators in immuno-oncology and immunology. Broad training in modern biology is offered with special emphasis on genetic, molecular, cell biological and structural approaches to the solution of problems in immuno-oncology and immunology. This training grant is a focus for training and research by 22 faculty members in the Departments of Microbiology & Immunology, Biochemistry, Cell Biology, Developmental and Molecular Biology, Gynecologic Oncology, Nuclear Medicine, OB/GYN, Pathology and Pediatrics. A vital component of our research and training environment is our well-established AECOM Cancer Center headed by Dr. I. David Goldman. All our trainers are members. Our predoctoral program operates within the guidelines of the Sue Golding Graduate School. The program contains the essential elements of a careful admissions process, a core of basic courses followed by specialized courses in immunology and supplemented with seminars, journal clubs, work-in-progress sessions, outside speakers, as well as close supervision of the research program for each student at both predoctoral and postdoctoral level. Establishment of the Belfer Institute for Advanced Biomedical Studies assures that the special concerns of postdoctoral associates are addressed concerning their research experience and career opportunities. The most important feature of our training program is the intensive work in the laboratory by predoctoral and postdoctoral trainees that starts with arrival and continues under close supervision throughout. Our program also features training in relevant instrumentation contained in shared facilities including a Hybridoma facility, FACS facility, transgenic mouse and stem cell facility, X-ray crystallography and molecular modeling, peptide synthesis and protein sequencing, oligonucleotide synthesis and DNA sequencing and microarrray facilities. For the next 5 years, we stress continued emphasis on cancer relevant research and a new focus on translational and clinical research.