Data Communication with Implantable Micro Devices

超出所提供的空间。 这个生物工程项目的主要目标是研究电源和数据通信，这是神经植入设备的常见功能。尽管研究界在神经工程和神经接口方面取得了重大进展，但这些领域的科学成果尚未大规模转化为临床应用。在电源和通信元器件的工程设计中存在着几个关键问题。目前在神经刺激器中使用大电池排除了使用先进的微电子器件使这些装置最小化的可能性，由于使用连接在胸部和头部之间的皮下电缆束而导致装置相关的并发症，并且由于需要手术更换电池而给患者带来高成本。尽管穿透皮肤的导线和磁感应都已被用于与可植入设备的通信，但它们存在引起感染（对于导线连接）和短信号传输距离（对于磁感应）的问题。如果不解决这些问题，许多有前途的神经植入物将继续只存在于研究实验室中，无法帮助数百万患有各种神经系统疾病的患者。 我们将开发在临床应用中可行、长期运行可靠、具有成本效益、方便患者的电源和通信平台，为患者提供最佳的生活质量。虽然我们的平台技术将针对一般应用，但要构建的原型将专门应用于脑深部电刺激。这些原型将在实验室动物上进行评价。我们的长期目标是将平台技术应用于人类，以治疗广泛的神经系统疾病。性能现场=

EXCEED THE SPACE PROVIDED. The primary goal of this bioengineering project is to investigate power supply and data communication which are common functions of neural implantable devices. Despite significant progress made by the research community in neuroengineering and neural interfaces, a large-scale transformation of scientific results in these fields to clinical applications has not yet taken place. Several critical problems exist in the engineering designs of power supply and communication components. The current use of a large battery in neural stimulators rules out minimization of these devices using advanced microelectronics, causes device-related complications due to the use of subcutaneous cable harness connecting between the chest and the head, and imposes high costs to the patients due to the requirement of surgical replacements of batteries. Although wires penetrating the skin and magnetic induction have both been utilized for communication with implantable devices, they have problems in causing infection (for wire connection) and short signal transmission distance (formagnetic induction). Without solving these problems, many promising neural implants will continue to exist only in research laboratories, unable to help millions of patients suffering from various neurological diseases. We will develop power supply and communication platforms that are feasible in clinical application, reliable in long-term operation, cost-effective, and convenient to patients in proving them with the best possible quality of life. Although our platform technologies will target the general application, the prototypes to be built will be specifically applied to deep brain stimulation. These prototypes will be evaluated on laboratory animals. Our long-term goal is to apply the platform technologies to humans for treatment of a broad class of neurological disorders. PERFORMANCE SITE ========================================Section End===========================================