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Biomimetic Self-Adhesive Dry EEG Electrodes

仿生自粘干式脑电图电极

基本信息

批准号：
8707451
负责人：
MINGUI SUN
金额：
$ 35.66万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-08-15 至 2016-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8707451
关键词：
Adhesives Air Animals Athletic Biomedical Engineering Biomimetics Brain Clinical Collodion Computer Systems Data Deterioration Development Devices Diagnostic Effectiveness Electrical Resistance Electrocardiogram Electrodes Electroencephalogram Electrolytes Electromyography Electronics Electroplating Environment Evaluation Family member Future Gel Glues Hair Health Care Costs Heating Home environment Human Laboratories Laboratory Finding Manuals Measures Mechanics Methods Modality Monitor Motion Muscle Nanotechnology Nerve Neurologic Office Management Pain Patients Performance Physiological Polysomnography Procedures Process Production Research Research Project Grants Role Sampling Scalp structure Signal Transduction Skin Sodium Chloride Solutions Staging Surface Synthesis Chemistry System Techniques Technology Time Tissues Toes Translating Travel Universities Validation Wireless Technology Zinc Oxide base biological systems brain computer interface clinical practice computerized data processing cost design design and construction electric impedance engineering design falls human subject improved insight interest man nanowire novel real world application sensor signal processing telehealth tool

项目摘要

Biomimetic Self-Adhesive Dry EEG Electrodes This three-year, non-hypothesis driven, biomedical engineering project aims to develop a novel skin-surface electroencephalogram (EEG) electrode. This new electrode does not require application of electrolyte; is able to penetrate scalp hair easily during electrode placement; can be quickly applied and removed; has low and stable electrode impedance; and has an extraordinary ability to self-adhere to the scalp without glue or tape. Its unconventional design is inspired from a biological system (the toe of geckos) which has shown clear effectiveness in the natural environment. Our design will be implemented by modern manufacturing techniques such as photolithography and wet chemistry synthesis which promise future mass production of the new electrode at low cost. The electroencephalogram (EEG) provides a unique window to observe the functional activity within the brain. The EEG is also a key technology utilized in non-invasive brain-computer interfaces which have generated tremendous research interests in recent years. As the EEG evolves from its traditional role as a neurological diagnostic modality in clinical laboratories to an important brain signal that interfaces with a variety of man-made systems in both clinical and non-clinical settings, both the signal acquisition and data processing methods have improved rapidly. In contrast to these scientific and technological advances, the procedures for affixing EEG electrodes to the scalp have not advanced adequately. These manual procedures are long and tedious for EEG technicians, and are uncomfortable and sometimes painful for patients because of the requirement to remove the top skin layer which has a high electrical resistance. The labor and facility usage costs for electrode installation are a significant portion of the total cost for clinical EEG studies, and the acceptance of EEG in non-clinical settings (e.g., home based monitoring, sleep study, and brain-computer interface) has been hindered significantly. This research will provide an effective solution to this long-standing EEG electrode placement problem. We will construct a biomimetic electrode, called the GT electrode, using advanced mechanical processing and nanotechnology, and conduct a two-stage validation of the new design. In order to translate our laboratory findings to successful clinical practice, we will also investigate methods to apply GT electrodes to the existing EEG systems.

仿生自粘性干脑电图电极这个为期三年的非假设驱动的生物医学工程项目旨在开发一种新的皮肤表面脑电图（EEG）电极。这种新电极不需要应用电解质;在电极放置期间能够容易地渗透头皮毛发;可以快速应用，去除;具有低而稳定的电极阻抗;并具有非凡的自粘附能力，头皮没有胶水或胶带。其非传统的设计灵感来自于一个生物系统（脚趾）。壁虎），在自然环境中表现出明显的效果。我们的设计将是通过诸如光刻和湿化学的现代制造技术来实现合成，这保证了未来以低成本大规模生产新电极。脑电图（EEG）为观察脑功能活动提供了一个独特的窗口在大脑中。脑电也是无创脑机接口的关键技术近年来引起了巨大的研究兴趣。随着脑电图从其传统的作用，作为一个重要的大脑信号的临床实验室的神经诊断方式在临床和非临床环境中与各种人造系统连接，信号采集和数据处理方法得到了迅速改进。与这些科学和技术进步相比，头皮上的电极没有充分推进。这些手工操作的过程冗长而乏味对于EEG技术人员来说，这是不舒服的，有时会让患者感到疼痛，因为这需要去除具有高电阻的顶部表层。劳动力和设施电极安装的使用成本是临床EEG研究的总成本的重要部分，以及EEG在非临床环境中的接受（例如，家庭监测、睡眠研究，以及脑机接口）已经受到严重阻碍。本研究将为这一长期存在的脑电电极放置问题提供有效的解决方案问题.我们将使用先进的机械，加工和纳米技术，并进行两阶段的新设计验证。为了将我们的实验室发现转化为成功的临床实践，我们还将研究应用于 GT电极到现有EEG系统。