Postdoctoral Training in Renal Diseases and Hypertension

描述（由申请人提供）：肾脏疾病和高血压是主要的、日益严重的公共卫生问题，是“2010年健康人”议程的目标。全国担心，新培训的学术科学家人数不足，无法在这些领域取得重大进展并发挥领导作用。因此，肾脏疾病和高血压奖学金培训计划代表了德克萨斯大学休斯顿健康科学中心学术组成部分的成功教师的合作努力，为优秀的学术型博士后研究员提供肾脏疾病和高血压的密集基础或临床研究培训。一个由资深科学家和医生科学家组成的富有成效的协作小组，他们具有互补的兴趣，并对导师和培训作出了明确的承诺，将担任四名博士后研究员的导师。学院实验室提供肾脏学和高血压重要领域的研究经验，包括上皮转运生理学和生物学，血管和肾细胞信号传导，血管生物学，免疫介导的损伤，组织限制性基因表达，高血压治疗的人体临床试验，以及人类高血压和糖尿病的遗传学和药物基因组学。该计划提供基础和最先进学科的培训和教学指导，包括分子，细胞和结构生物学，分子遗传学，生物化学，转基因技术，电生理学，免疫学，功能基因组学，基因传递，生物统计学和流行病学。受训人员还将受益于得克萨斯州医疗中心的大量资源和该地区大量的高危或受影响患者。所有被录取的申请人都必须坚定地致力于学术调查的职业生涯和培训计划的目标。医学博士实习生学位将追求一个计划，包括一年的临床培训，这是不支持的补助金，并至少两年的研究培训将由本申请的资金支持。博士申请人将被要求有先前的研究经验，这可能是在非肾脏领域，和优秀的参考。所有受训人员将被要求参加具体的课程，解决研究方法，实验设计，研究诚信和道德。将重视和鼓励来自不同背景的受训人员参加。该计划的目标是，其毕业生将为新一代学术肾病学家和肾脏研究人员做出贡献，以解决肾脏疾病和高血压的挑战性问题

DESCRIPTION (provided by applicant):Kidney disease and hypertension are major, growing public health problems that are targeted in the "Health People 2010" agenda. There is national concern that the number of newly trained academic scientists equipped to make major advances and to assume leadership roles in these areas will be inadequate. Accordingly, the Fellowship Training Program in Renal Diseases and Hypertension represents a cooperative effort of accomplished faculty from the academic components of The University of Texas Health Science Center at Houston to provide to outstanding, academically-oriented postdoctoral fellows intensive basic or clinical research training in renal disorders and hypertension. A productive and collaborative group of senior scientists and physician-scientists with complementary interests and a demonstrated commitment to mentorship and training will serve as mentoring faculty to four postdoctoral fellows. The faculty laboratories offer research experience in important areas of nephrology and hypertension, including, epithelial transport physiology and biology, vascular and renal cell signaling, vascular biology, immunologically mediated injury, tissue-restricted gene expression, human clinical trials in the treatment of hypertension, and the genetics and pharmacogenomics of human hypertension and diabetes. The program provides training and didactic instruction in fundamental and state-of-the-art disciplines, including molecular, cell, and structural biology, molecular genetics, biochemistry, transgenic technologies, electrophysiology, immunology, functional genomics, gene delivery, biometry, and epidemiology. The trainees will also profit from the substantial resources of the Texas Medical Center and the enormous population of at-risk or affected patients in the area. All applicants accepted into the program must have a firm commitment to a career in academic investigation and to the goals of the Training Program. Trainees with M.D. degrees will pursue a program consisting of one year of clinical training, which is not supported by this grant, and at least two years of research training to be supported by funds from this application. Ph.D. applicants will be required to have prior research experience, which can be in non-renal fields, and outstanding references. All trainees will be required to attend specific courses addressing research methodology, experimental design, research integrity, and ethics. Representation by trainees from diverse backgrounds will be valued and encouraged. It is the goal of the Program that its graduates will contribute to a new generation of academic nephrologists and renal investigators equipped to address the challenging problems in renal diseases and hypertension