Safe Use of Medications in Primary Care Practices

描述（由申请人提供）：用药错误是一种常见的医疗错误，带来了巨大的社会负担。据估计，每年有770，000名美国人经历导致伤害或死亡的药物不良事件，总成本为20亿美元。这些统计数据使减少用药错误成为国家的优先事项。由于门诊处方的药物数量，以及大多数关于用药错误的数据来自住院患者，医学研究所呼吁对门诊用药错误进行更多的研究。此K08申请概述了一个五年计划，以支持候选人谁是已经有助于门诊药物安全的临床研究。候选人是一名临床药剂师，拥有10年的工作经验和初级保健专业培训，并得到了学术部门的大力支持。此外，她在药物治疗教学和药物安全性实践研究方面有丰富的经验。职业发展计划提供了一系列精心挑选的培训和指导经验，包括博士水平的卫生服务研究课程，指导研究导致合作研究和出版物，以及专业网络，这将使她的研究成果达到一个新的水平。她提出的研究计划，在初级保健实践中安全使用药物，有三个具体目标：1）确定示范性的方法和范例的药物和解（即，捕获和解决实际服用的药物与患者病历中记录的药物之间的差异）; 2）评估初级保健患者服用多种药物的药物核对示范方法的可行性;以及3）传播研究结果，并在进行结果试验的建议中扩大这项工作的范围。

DESCRIPTION (provided by applicant): Medication error, a common type of medical error, carries a tremendous social burden. An estimated 770,000 Americans each year experience adverse drug events that result in injury or death at a total cost of $2 billion. These statistics have made the reduction of medication errors a national priority. Because of the number of medications prescribed in the outpatient setting and because most data on medication errors come from the inpatient setting, the Institute of Medicine has called for more research on medication errors in the outpatient setting. This K08 application outlines a five-year plan to support a candidate who is already contributing to clinical research on outpatient medication safety. The candidate is a clinical pharmacist with 10 years of working experience and specialty training in primary care and strong support from her academic department. In addition, she has substantial experience teaching pharmacotherapy and conducting practice-based research on medication safety. The career development plan provides a sequence of carefully selected training and mentoring experiences, including doctoral-level health services research coursework, mentored research leading to collaborative studies and publications, and professional networking, that will catapult her to the next level of research achievement. Her proposed research program, Safe Use of Medications in Primary Care Practices, has three specific aims: 1) to identify exemplary methods and exemplars for medication reconciliation (i.e., capturing and resolving discrepancies in the medications actually being taken and those recorded in patients' medical records); 2) to evaluate the feasibility of exemplary methods for medication reconciliation on primary care patients taking multiple medications; and 3) to disseminate study results and to extend the scope of this work in proposals to conduct outcomes trials.