Resource and QOL Consequences of Lung Cancer Screening

描述（由申请人提供）：本提案的主要目的是为候选人提供实现以下目标的方法，指导和结构。 中期目标是测量使用低剂量螺旋计算机断层扫描（CT）筛查肺癌的心理、生活质量和资源效应，以及影响随访建议依从性的因素。 长期目标是成为一个独立的健康服务研究人员，专注于评估癌症筛查计划和促进癌症筛查中的个人决策。 候选人将进一步发展和利用心理测量和分析，癌症流行病学和癌症筛查技术，以及通过医疗索赔数据库评估医疗资源利用率的研究技能。 职业发展计划将包括正式的课程工作，在特定的方法领域，临床 通过导师和国家癌症研究所癌症预防和控制夏季课程、会议和研讨会以及研究进行培训。 拟议研究的主要目标是衡量参与肺癌筛查计划的个人的心理和资源利用后果，以及对筛查后续建议的遵守情况。 肺部CT筛查的临床益处尚不确定。 然而，筛查CT检测到约40%的所有筛查个体的异常。 为了评价和改进肺部CT筛查方案，并促进有关筛查的知情决策，必须确定筛查的非临床效果。 拟议的研究将从NCI-funded SPORE项目中招募患者，该项目涉及筛查肺部CT的临床结果（Joel Weissfeld，P.I.，匹兹堡肺筛查研究）。 将随着时间的推移收集心理特征和医疗护理使用的自我管理调查、医疗索赔数据和来自PLuSS研究的数据。 拟议的K 07研究将确定1）参与肺癌筛查的心理和资源影响，2）这些影响如何随筛查结果和个体特征而变化，以及3）个体是否在筛查后坚持推荐的随访以及影响不坚持的因素。

DESCRIPTION (provided by applicant): The primary purpose of this proposal is to provide the candidate with the means, mentorship and structure to achieve the following goals. The intermediate goal is to measure the psychological, quality of life and resource effects of screening for lung cancer using low dose spiral computed tomography (CT), as well as factors affecting adherence to follow up recommendations. The long term goal is to become an independent health services researcher focusing on evaluation of cancer screening programs and promotion of individual decision making in cancer screening. The candidate will further develop and utilize research skills in psychological measurement and analysis, cancer epidemiology and cancer screening techniques, and assessment of health care resource utilization through medical claims databases. The career development program will incorporate formal course work, tutorials with experts in specific methodological fields, clinical training through preceptorships and the National Cancer Institute Cancer Prevention and Control summer course, conferences and seminars, and research. The major goal of the proposed research is to measure the psychological and resource utilization consequences for individuals participating in a lung cancer screening program, and adherence to follow up recommendations from screening. The clinical benefits of screening lung CT are as yet uncertain. However, screening CT detects abnormalities in approximately 40% of all screened individuals. To evaluate and improve screening lung CT programs, and to promote informed decision making concerning screening, it is essential to determine the non-clinical effects of screening. The proposed research will recruit patients from an NCI-funded SPORE project on the clinical outcomes of screening lung CT (Joel Weissfeld, P.I., Pittsburgh Lung Screening Study). Self-administered surveys of psychological characteristics and medical care use, medical claims data, and data from the PLuSS study will be collected over time. The proposed K07 research will determine 1) the psychological and resource effects of participating in lung cancer screening, 2) how these effects vary with screening results and individual characteristics, and 3) whether individuals adherence to recommended follow up after screening and what factors affect non-adherence.