A PROSPECTIVE STUDY OF CHILDREN OF SCHIZOPHRENIC PARENTS

产品说明：（申请人提供）：NYHRP的最后阶段将集中于通过以下方式有序地完成这项纵向研究：1）准备并将NYHRP从1971年开始到2005年完成的整个数据库放入档案库，以实现数据共享; 2）进行电话汇报，向600多名参与者（父母，目标，纽约人权方案每年定期与这些人联系，并在接到电话后写信，附上纽约人权方案社会工作者习惯于提供的转介和其他援助资源清单。此外，将执行目前正在进行中的其余三个目标。这些措施是：（3）完成翻译对于所有接受Axis I作为主要诊断的参与者，将RDC诊断（再诊断）为DSM-IV;共病疾病也将被翻译为DSM-IV; 4）完成从选定家庭收集血液或口腔拭子样本，用于提取和保存DNA，以便可能用于未来研究; 5）完成手稿，准备作为同行评审的出版物提交。

DESCRIPTION: (provided by applicant): This final phase of the NYHRP will focus on bringing this longitudinal study to an orderly conclusion by 1) preparing and placing in an archival respository the entire databank of the NYHRP from its start in 1971 to its completion in 2005, for the purpose of data sharing and 2) carrying out debriefing telephone calls to say good bye to each of the 600+ participants (parents, Targets, Siblings) with whom the NYHRP has been in regular annual contact and following the calls with a letter accompanied by a list of resources for referrals and other assistance that the NYHRP social workers have been accustomed to provide. Additionally, three remaining goals that are now in midprocess will be carried out. These are: 3) completion of the translation (rediagnosis) of RDC to DSM-IV diagnoses for all participants who have received Axis I as primary diagnosis; comorbid disorders will also be translated to DSM-IV; 4) completion of the collection of blood or buccal swab samples from selected families for extraction and preservation of DNA for probable use in future studies; 5) completion of manuscripts in preparation for submission as peer-reviewed publications.