Core D--Skills Development

这个应用程序是为临床研究技能发展核心基于心脏登记处在儿童医院，波士顿。自1965年成立以来，该登记处在培训在儿科先天性心脏病学术生涯中取得成功的个人方面有着良好的记录。例如，这个项目的一些高级研究员有机会在心脏登记处轮岗，或者是心脏登记处的研究员。本核心的广泛目标是提供一个支持研究人员职业发展的环境。核心的主要特点包括强调人类心脏解剖和先天性心脏病，强调综合病理生理学方法，以及与SCCOR组成部分的强相互作用。它的前提是详细了解人类先天性心脏病的病理将为后续的临床或调查工作提供重要的基础。教师包括心脏登记处的工作人员，他们提供经典心脏病理学方面的专业知识，以及使用现代分子和细胞生物学方法研究先天性心脏病的SCCOR研究人员。培训计划的结构旨在为受训者提供访问心脏登记处及其大量资源的机会。学员将参与心脏解剖、会诊病例，广泛使用先心病标本采集教学标本，利用先心病病理学系列视频节目，参加教务处教师主持的讲座和会议。通过参加临床和研究会议，期刊，进一步加强培训经验

This application is for a Clinical Research Skills Development Core based in the Cardiac Registry at Children's Hospital, Boston. Since its inception in 1965, the Registry has a strong record of training individuals who have been successful in academic careers in pediatric congenital heart disease. For instance, several of the senior investigators of this program have had a chance to rotate in the Cardiac Registry, or have been Cardiac Registry fellows. The broad objective of this Core is to provide an environment that supports career development of the investigators. The key features of the Core include an emphasis on human cardiac anatomy and congenital heart disease, an emphasis on integrative pathophysiologic approaches, and strong interactions with components of the SCCOR. It is based on the premise that a detailed understanding of the pathology of human congenital heart disease would provide an important foundation for subsequent clinical or investigative work. The faculty consists of the staff of the Cardiac Registry, who provide expertise in classic cardiac pathology, as well as SCCOR investigators using modern molecular and cell biologic approaches to study congenital heart disease. The structure of the training program is designed to provide trainees with access to the Cardiac Registry and its considerable resources. Trainees will participate in cardiac autopsies, consultation cases, and make extensive use of the teaching specimens in the congenital heart collection, utilize the video program series on the pathology of congenital heart disease, and participate in lectures and conferences led by the faculty of the Registry. The training experience is further enhanced by attendance in clinical and research conferences, journal clubs and formal seminars in the Departments of Pathology, Cardiology, and Surgery, as well as in the Harvard Medical School campus. Trainees are to be selected from all members of this SCCOR program, as well as similar clinical programs nationwide, with an emphasis on identifying and recruiting under-represented minorities. This Core should provide basic information about human congenital heart disease that enhances the experience of the young investigators.