Extramural Research Facilities Improvement Program "Dru*

描述(由申请人提供)： 这项申请的目的是获得配套资金，以整合和扩大宾夕法尼亚州立大学医学院(PSUCOM)现有的药物发现核心设施(DDCF)的空间。药物发现和开发是基础生物医学研究的自然延伸，PSUCOM的许多教职员工正在进行具有开发预防、诊断或治疗药物的强大潜力的研究。虽然DDCF是一个成立的单位，并得到PSUCOM管理部门的持续支持，但本申请中申请的资金将提供以下资源：1.整合和整合支持药物发现和开发的现有和计划的共享资源。2.满足资助调查人员的空间要求，同时培养药物发现计划的机构身份。3.创造DDCF相关基础设施的扩展潜力。4.创建毗连的办公空间，以提供专用的数据分析工作站，促进合作。5.为DDCF的教职员工和学生用户创造公共空间。6.建立实验室和办公场所，加强对学生、博士后研究员和教师的培训。7.促进PSUCOM教职员工报告发现并促进技术转让。这项申请寻求资金，以翻新PSUCOM生物医学研究大楼二楼的6600平方英尺的设施，靠近1700平方英尺的办公和协作工作空间，以支持药物发现计划。资助这项申请将对PSUCOM将基础研究转化为临床应用产生重大积极影响。

DESCRIPTION (provided by applicant): The objective of this application is to obtain matching funds to integrate and enlarge space for the existing Drug Discovery Core Facility (DDCF) of the Pennsylvania State University College of Medicine (PSUCOM). Drug discovery and development are the natural extension of basic biomedical research, and many faculty members at PSUCOM are conducting research with strong potential for the development of preventative, diagnostic or therapeutic agents. While the DDCF is an established unit and enjoys the ongoing support of PSUCOM administration, the funding requested in this application will provide the resources to: 1. Consolidate and integrate existing and planned shared resources that support drug discovery and development. 2. Meet space requirements for funded investigators, while fostering an institutional identity for the Drug Discovery Program. 3. Create expansion potential for DDCF-related infrastructure. 4. Create contiguous office space to provide dedicated data analysis workstations and to promote collaboration. 5. Create communal space for faculty and student users of the DDCF. 6. Establish laboratory and office space to enhance the training of students, postdoctoral fellows and faculty. 7. Facilitate reporting of discoveries by PSUCOM faculty and promote technology transfer. This application seeks funding to renovate a 6,600 square foot facility on the second floor of the Biomedical Research Building of the PSUCOM, in close proximity to 1,700 square feet of office and collaborative workspace, to support the Drug Discovery Program. Funding this application will have a major positive impact on the translation of basic research to clinical application within the PSUCOM.