Xth International Workshop on Plasminogen Activation

描述(申请人提供)：细胞外蛋白分解的调控，特别是纤溶酶原激活，是科学研究、临床医学和生物技术之间快速发展的领域。基础实验室的贡献对止血领域的新疗法的开发具有独特的重要意义，包括重组tPA和其他溶栓剂以及重组凝血因子。自1985年创办以来，纤溶酶原激活的分子和细胞生物学国际研讨会一直被科学界认为是纤溶酶原激活领域和细胞外蛋白分解领域科学交流的核心，吸引了150-200名科学家。第X届国际研讨会将于2005年4月9日至13日在马里兰州波托马克市的博尔格中心举行。这次会议是独一无二的，因为它完全由提交的摘要中的口头和海报陈述组成。提交的摘要的海报将在整个会议期间张贴，以最大限度地提供查看和讨论当前工作的机会。会议提出了12个口头会议，包括：1)纤溶酶原激活系统在心脏和血管疾病中的作用；2)纤溶酶原激活系统在肺纤维化和其他肺部疾病中的作用；3)蛋白水解酶和蛋白水解酶受体在细胞迁移和黏附中的作用；4)新型膜丝氨酸蛋白酶；5)结构和功能研究的新发现；6)纤溶酶原激活系统在组织修复和组织重塑中的作用；7)蛋白水解酶在肿瘤血管生成和转移中的作用；8)蛋白水解酶在炎症和恶性进展中的作用；9)神经生物学中的蛋白酶、蛋白水解酶抑制物和细胞受体；10)神经病理学中的纤溶酶原激活系统；11)微生物纤溶酶原激活和疾病；和12)治疗的发展和在溶栓方面的应用；会议将由该领域的杰出领导人主持。纤溶酶原激活的分子和细胞生物学国际研讨会长期致力于支持科学多样性，并致力于将少数族裔和妇女纳入该计划。在目前的方案中，42%的主席是女性(摘要结束)。

DESCRIPTION (provided by applicant): The regulation of extracellular proteolysis in general and plasminogen activation in particular are rapidly moving fields at the interface of scientific research, clinical medicine, and biotechnology. Contributions from the basic laboratory have been uniquely important for the development of new therapies in the field of hemostasis, including recombinant tPA and other thrombolytics as well as recombinant clotting factors. Since its inception in 1985 the International Workshop on Molecular and Cellular Biology of Plasminogen Activation has been recognized by the scientific community as the core of scientific exchange in the plasminogen activation field and in extracellular proteolysis as well and attracts between 150 - 200 scientists. The Xth International Workshop will be held at the Bolger Center in Potomac, Maryland on April 9-13, 2005. The meeting is unique as it consists exclusively of oral and poster presentations from submitted abstracts. Posters of submitted abstracts remain up for the entire meeting to maximize opportunities for viewing and discussing current work. The meeting proposes 12 oral sessions which include: 1) Role of plasminogen activation system in cardiac and vascular diseases; 2) Plasminogen activation system in pulmonary fibrosis and other lung diseases; 3) Proteases and protease receptors in cell migration and adhesion; 4) Novel membrane serine proteases; 5) Novel findings from structure and function studies; 6) Plasminogen activator system in tissue repair and tissue remodeling; 7) Proteases in tumor angiogenesis and metastasis; 8) Proteases in inflammation and malignant progression; 9) Proteases, protease inhibitors and cellular receptors in neurobiology; 10) The plasminogen activation system in neuronal pathology; 11) Microbial plasminogen activation and disease; and 12) Therapeutic developments and applications in thrombolysis; Sessions will be chaired by distinguished leaders in the field. The International Workshop on Molecular and Cellular Biology of Plasminogen Activation has a longstanding commitment to supporting diversity in the sciences, and is committed to the incorporation of minorities and women in the program. In the current program, 42% of the chairs are women (End of abstract).