Pesticide Exposure Pathways

描述（由申请方提供）：儿童易感性的暴露机制由暴露类型和频率、年龄特异性行为以及时间和毒代动力学暴露考虑因素定义。农药暴露途径研究项目侧重于儿童农药暴露的生理和行为机制。这些详细的评估与其他基于现场和实验室的中心项目非常吻合。基于社区的预防性研究项目正在评估儿童通过职业带回家和饮食接触而接触的机制。他们的评估与农药接触途径项目详细的喷雾漂移和活动模式评估非常吻合。这两个项目将共同为接触评估和风险表征核心提供信息，并为基于实验室的研究提供现实环境。该项目的结果将反馈给以社区为基础的预防性研究项目，并为风险表征和社区外联和翻译核心的活动提供信息，以减少风险。

Description (provided by applicant): Mechanisms of exposure for children's susceptibility are defined by types and frequency of exposures, age-specific behaviors, and temporal and toxicokinetic exposure considerations. The Pesticide Exposure Pathways Research Project focuses on the physical and behavioral mechanisms of children's pesticide exposures. These detailed assessments fit well with the other field and laboratory-based Center projects. The Community-Based Participatory Research Project is evaluating the mechanisms of children 's exposure through occupational takehome and dietary exposures. Their assessments fit well with the detailed spray drift and activity pattern assessments of the Pesticide Exposure Pathways Project. Together, both projects will inform the Exposure Assessment and Risk Characterization Cores and provide a real-life context for the laboratory-based studies. The results of this project will feed back to inform the Community-Based Participatory Research Project and also inform the activities of the Risk Characterization and the Community Outreach and Translation Cores to reduce exposures.