Training Cardiovascular Biology: PREDOCTORAL

描述(由申请人提供)： 这是一项博士前培训计划的新申请，该计划旨在每年培训5名对心血管系统感兴趣的研究生。心血管疾病是美国死亡和发病的主要原因，因此需要在基础研究方面做出重大努力。该培训计划将为未来科学家的培训提供一种形式，这些科学家将投入时间和精力开发研究和控制疾病的工具。这项申请的主要目标是为博士和医学博士候选人建立一个正式的研究和学术培训计划，这些候选人是从医学院的总申请者中精心挑选出来的，从而吸引有能力的年轻科学家对心血管研究的关注，引导他们进入生物医学研究领域。将提供与心血管疾病相关的培训，包括动脉粥样硬化、心力衰竭和高血压，并应用生理学、药理学、病理学、生物化学、遗传学和分子生物学等学科。课程还将包括心血管生物学的特别课程，重点是基础研究、疾病机制和临床相关性。学员将参加惠特克的各种活动 心血管研究所(CVI)在我们研究所。培训学院隶属于基础科学系和CVI。培训计划的成员之间有很强的研究互动。每个教员都有教授研究生课程的经验，大多数人都有过许多后来担任过学术职位的实习生，而且每个人都至少有一项来自NIH的有效拨款。拟议的项目可能是独一无二的，因为它将提供一个机会，在学术环境中培训转译和基础心血管研究研究员，在这种学术环境中，可以获得大量经验，心血管生物学的尖端资助研究正在进行，并且对毕业生的需求敏感。 学生是由学术导师提供的。

DESCRIPTION (provided by applicant): This is a new application for a PREDOCTORAL training program designed to train yearly five graduate students interested in the cardiovascular system. Cardiovascular diseases represent the major causes of mortality and morbidity in the United States, and thus require major efforts in fundamental research. The training program will provide a format for the training of future scientists who will devote time and efforts in developing the tools to study and control the disease. The major goal of this application is to establish a formal research and academic training program for Ph.D. as well as M.D.-Ph.D. candidates that have been carefully selected from a total pool of applicants to the medical school, thus capturing attention of competent young scientists to cardiovascular research, leading the way to a career in biomedical research. Training will be offered in topics related to cardiovascular disease including atherosclerosis, heart failure and hypertension, with application of disciplines as physiology, pharmacology, pathology, biochemistry, genetics and molecular biology. The curriculum will also include special courses in cardiovascular biology, with a focus on basic research, mechanism of disease and clinical relevance. Trainees will participate in various activities of the Whitaker Cardiovascular Institute (CVI) at our institute. The training faculty is affiliated with basic science departments and with the CVI. There are strong research interactions between members of the training program. Each faculty has experience in teaching graduate courses, most have had numerous trainees that have gone on to hold academic positions, and all have at least one active grant from NIH. The proposed program may be unique in that it will provide an opportunity to train predoctoral fellows in translational and basic cardiovascular research in an academic setting in which considerable experience is available, where cutting-edge funded research in cardiovascular biology is ongoing, and where sensitivity to the need of graduate students is provided by an academic mentor approach.