MULTIDISCIPLINARY PRE-DOCTORAL TRAINING IN INTEGRATIVE CARDIOVASCULAR BIOLOGY

描述（由申请人提供）：此申请是乔治亚医学院（MCG）综合心血管生物学多学科博士前培训补助金的竞争性更新。该计划的长期目标是培养博士预科博士和医学博士/博士。学生将在综合心血管生物学方面进行独立研究，利用分子，遗传，细胞，组织/器官，整个动物和人类实验方法。该项目涉及细胞生物学与解剖学、医学、病理学、儿科、药理学与毒理学、生理学、外科等28个系的专家。这些教师中的大多数还与乔治亚预防研究所、分子医学和遗传学研究所以及MCG校园的血管生物学中心有联系或有联系。该计划的教师导师代表了一群杰出的综合性心脏和血管生物学家，他们的研究兴趣涵盖五个相关的心血管领域：1)血管细胞信号传导，2)血管张力控制，3)心脏发育，4)内皮功能障碍，5)心血管疾病预防。这项培训经费将通过医学院血管生物学中心进行管理。该项目由项目主任大卫·m·波洛克博士和项目联合主任詹妮弗·s·波洛克博士指导，他们都是知名的调查员。由乔治亚医学院研究生项目经验丰富的领导组成的内部咨询委员会将监督该项目。受训者将是博士或医学博士。目前在乔治亚医学院研究生院攻读生物医学科学博士学位的全日制研究生。学生将根据他们对综合心血管生物学的兴趣以及他们以前的学术表现和研究经验进行选择。所有受训人员都必须参加教学培训活动，包括第一年的核心课程和通过第一次资格考试；高级选修课程，如心血管生理学与药理学、血管生物学前沿；科学传播与研究伦理、生物统计学课程；参加一个或多个部门系列研讨会；心血管杂志俱乐部；以及一年一度的研究生研究日活动。完成课程后，学生将准备在一流的实验室进行博士后培训，开始他们作为心血管科学独立研究者的职业生涯。

Description (provided by applicant): This application is a competing renewal of a multidisciplinary pre-doctoral training grant in integrative cardiovascular biology at the Medical College of Georgia (MCG). The long-term objective of this program is to train pre-doctoral Ph.D. and M.D./Ph.D. students for independent research careers in integrative cardiovascular biology, utilizing molecular, genetic, cellular, tissue/organ, whole animal and human experimental approaches. This program involves the expertise of 28 faculty in the Departments of Cell Biology & Anatomy, Medicine, Pathology, Pediatrics, Pharmacology & Toxicology, Physiology, Surgery. A majority of these faculty also have appointments or affiliations with the Georgia Prevention Institute, the Institute for Molecular Medicine and Genetics, and the Vascular Biology Center on the MCG campus. The faculty preceptors of the program represent an outstanding group of established integrative cardiac and vascular biologists whose research interests cover five related cardiovascular areas: 1) vascular cell signaling, 2) control of vascular tone, 3) cardiac development, 4) endothelial dysfunction, and 5) prevention of cardiovascular disease. This training grant will be administered through the Vascular Biology Center in the School of Medicine. The program is directed by Dr. David M. Pollock, Program Director and Dr. Jennifer S. Pollock, Program Co- Director, both established investigators. An Internal Advisory Committee of experienced leaders of the graduate program at the Medical College of Georgia will supervise the program. Trainees will be Ph.D. or M.D./Ph.D. graduate students currently enrolled full-time in the Biomedical Sciences Ph.D. program in the Medical College of Georgia School of Graduate Studies. Students will be selected based on their expressed interest in integrative cardiovascular biology and their previous academic performance and research experience. All trainees will be required to participate in didactic training activities, which consist of the first year core curriculum and passing the first qualifying exam; advanced course electives such as Cardiovascular Physiology & Pharmacology and Frontiers in Vascular Biology; courses in Scientific Communications and Research Ethics, and Biostatistics; attendance in one or more departmental seminar series; the cardiovascular journal club; and the annual Graduate Research Day activities. Upon completion of the program, students will be ready to pursue post-doctoral training at premier laboratories as they begin their careers as independent investigators in cardiovascular sciences.