Training in Integrative and Systems Biology of Cardiovascular Disease

心血管疾病综合和系统生物学培训

• 批准号: 9359681
• 负责人: JEANNE M. NERBONNE
• 金额: $ 19.31万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9359681
• 关键词: Cardiovascular Diseases; Systems Biology; Training

This proposal seeks support for the Training in Integrative and Systems Biology of Cardiovascular Disease Training Program in the Center for Cardiovascular Research at Washington University. The goals of this Program are to provide predoctoral and postdoctoral trainees with: outstanding research opportunities; fundamental education and basic training in cardiovascular physiology, pathophysiology and disease mechanisms; opportunities to be introduced to, and potentially to participate in, translational cardiovascular research; and, mentoring to prepare them to be productive, independent scientists, educators and mentors. The critical components and the clear strengths of this Program are the twenty-one (21) participating faculty and the trainees themselves. Another clear strength of this Training Program is the highly interactive and collaborative environment in the Center for Cardiovascular Research, indeed at Washington University in general, which translates to expanded research, education, training and mentoring opportunities for all of our trainees. The participating training faculty derive from seven Departments and four Divisions within the Department of Internal Medicine, and includes nationally and internationally recognized leaders in the three research and training areas of emphasis in this Training Program: 1) Cardiac metabolism, remodeling and cardiomyopathies; 2) Ion channels, cardiac excitability and arrhythmias; and, 3) Vascular biology, inflammation and coronary disease. The participating faculty are all well-funded, highly interactive, collaborative and productive investigators who are all also committed to providing the training, experience, resources, intellectual enthusiasm, and mentoring needed to facilitate the scientific and professional development of the Program trainees. Importantly, the more experienced senior faculty participants are also committed to the mentoring of the more junior Training Program faculty preceptors. In addition to the research training provided in individual and collaborating laboratories, trainees in this Program will also participate in a “Core Curriculum in Integrative and Systems Cardiovascular Biology”, the weekly "Trainees in Cardiovascular Biology" and “Cardiovascular Research” seminar series, the biannual “Cardiovascular Training Program Distinguished Lectureship,” the annual “Cardiovascular Research Day”, and have the opportunity to participate in translational cardiovascular research. This Training Program also provides trainees with continuing instruction in Ethics and Research Science, and has outlined formal and informal mechanisms for helping trainees develop individualized educational, training and career development plans and for monitoring the progress, professional development and mentoring of each predoctoral and postdoctoral trainee. Formal mechanisms are also in place for evaluating, and evolving as needed, the Training Program itself going forward.

本提案旨在支持心血管综合和系统生物学培训 华盛顿大学心血管研究中心的疾病培训计划。的目标 该计划旨在为博士前和博士后学员提供：优秀的研究机会; 心血管生理学、病理生理学和疾病方面的基础教育和基本培训 机制;引入并可能参与转化性心血管疾病的机会 研究;以及指导，使他们成为富有成效的独立科学家、教育家和导师。 该计划的关键组成部分和明显的优势是二十一（21）参与教师 和受训者自己。该培训计划的另一个明显优势是高度互动， 在心血管研究中心的协作环境中，实际上是在华盛顿大学， 一般，这意味着扩大研究，教育，培训和指导的机会，为我们所有的 实习生参加培训的教师来自七个部门和四个司在 内科，包括国内和国际公认的领导人在三个 本培训计划的重点研究和培训领域：1）心脏代谢，重塑和 心肌病; 2）离子通道、心脏兴奋性和心律失常;以及，3）血管生物学、炎症 和冠心病。参与的教师都是资金充足，高度互动，协作， 富有成效的调查人员也都致力于提供培训，经验，资源，知识 积极性和指导，以促进该计划的科学和专业发展 实习生重要的是，更有经验的高级教师参与者也致力于指导 更初级的培训计划教师导师。除了个人提供的研究培训外， 和合作实验室，本计划的学员还将参加“综合核心课程”， 和系统心血管生物学”，每周“心血管生物学学员”和“心血管 研究”研讨会系列，一年两次的“心血管培训计划杰出讲师”， 每年的“心血管研究日”，并有机会参加翻译心血管 research.该培训计划还为学员提供道德和研究方面的持续指导 科学，并概述了正式和非正式的机制，帮助学员发展个性化的 教育、培训和职业发展计划，并监测进展情况、职业发展 并指导每一位博士前和博士后实习生。还建立了正式机制， 评估，并根据需要发展，培训计划本身向前发展。