Research Training in Child Psychopathology & Treatment

描述(由申请人提供)：这是一项为期5年的机构博士后研究培训计划的竞争更新，该计划针对患有严重精神障碍的儿童和青少年进行干预研究。该计划将解决这一领域缺乏训练有素的临床研究人员的问题。拟议方案的具体目标是在以下青年干预研究领域培训临床研究人员：评估新药物和/或心理社会治疗的疗效研究；在不同人群和环境中应用经验性支持的治疗的有效性研究；评估精神药物的安全性和不良影响，特别是在长期治疗期间；以及与干预研究相关的研究领域--仪器开发、功能神经成像和结果评估战略。该项目的教职员工包括6名初级导师和6名二级导师，他们在培训和指导博士后研究员方面拥有丰富的经验，并拥有既定的资助研究组合。该培训计划设在儿童和青少年精神病学部，与医学院、公共卫生学院和肯尼迪·克里格研究所(Kennedy Krieger Institute)等其他机构积极合作，肯尼迪·克里格研究所是一家专门研究发育障碍儿童的机构。 该培训项目借鉴了我们过去4年的经验，将有5个职位，并将包括博士(2年培训)和博士(3年)。将强调招募任职人数偏低的少数群体。 培训包括：1)核心课程工作，以确保对研究方法、设计和统计原则的基本理解；2)与主要导师合作监督临床研究；3)个人研究项目，为成功的职业发展奖或其他NIH拨款申请生成试点数据；4)研究研讨会，包括研究方案审查/批评、教学/正式报告和期刊俱乐部；以及5)出席国家专业会议并发表报告。培训将在致力于研究指导的多学科研究人员的支持性环境中进行。 这一培训计划是精心组织的，目的是培养一批毕业生，他们将成为儿童和青少年严重精神障碍的富有成效的独立干预研究人员。

DESCRIPTION (provided by applicant): This is a 5-year competitive renewal of an institutional post-doctoral research training program in interventions research in children and adolescents with major mental disorders. The program will serve to address the shortage of well-trained clinical researchers in this field. The specific aims of the proposed program are to train clinical researchers in the following areas of interventions research with youth: efficacy studies evaluating new medication and/or psychosocial treatments; effectiveness studies of empirically supported treatments applied in diverse populations and settings; evaluation of safety and adverse effects of psychotropic medications, particularly during long-term treatment; and related areas of study as they pertain to interventions research--instrument development, functional neuroimaging, and outcomes assessment strategies. The program faculty includes 6 primary mentors and 6 secondary mentors who have extensive experience in training and mentoring post-doctoral fellows and an established funded research portfolio. The training program is located in the Division of Child and Adolescent Psychiatry, with active collaborations elsewhere in the School of Medicine, the School of Public Health and the Kennedy Krieger Institute, an institution devoted to children with developmental disabilities. The training program, which draws upon our experience over the past 4 years, will have 5 positions, and will include Ph.D.s (for 2 years of training) and M.D.s (for 3 years). Recruitment of underrepresented minorities will be emphasized. Training consists of: 1) core coursework to ensure a basic understanding of the principles of research methods, design and statistics; 2) supervised clinical research in collaboration with a primary mentor, 3) an individual research project to generate pilot data for a successful career development award or other NIH grant application, 4) research seminars that involve study proposal reviews/critiques, didactics/formal presentations, and a journal club; and 5) attendance and presentations at national professional meetings. The training will occur in a supportive environment of multidisciplinary researchers who are committed to research mentoring. This training program is thoughtfully organized to produce a cadre of graduates who will become productive independent interventions researchers in child and adolescent major mental disorders.