INFECTIOUS DISEASES

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。沿着美国和墨西哥之间的边界地区是一个被称为“la frontera”的边界，发展中国家和发达国家在这里相遇，几乎在生活的各个方面都形成了一个独特的混合环境。这一地区是一个大熔炉，将边界两侧对人类健康的独特挑战结合在一起，成为一个双重危险的地区，人口面临两种环境弊病的风险。埃尔帕索的神经囊虫病和耐药结核病的发病率高于正常水平就是这种并列结果的两个例子。西德克萨斯沙漠地区的不断发展加剧了这一问题，使越来越多的人频繁接触新环境，增加了新疾病传播的机会。由于这些担忧，德克萨斯大学埃尔帕索分校的边境生物医学研究中心包括一个专门的传染病研究单位，以促进具有地区重要性的传染病研究项目的发展。除了继续支持现有的研究项目外，该提案还为UTEP新的生物科学研究大楼内的新的BSL3实验室研究设施提供设备和人员支持基础设施。这一安全设施将有助于开展研究项目，重点研究高级传染因子，特别是耐药结核分枝杆菌

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The region along the Border between the United States and Mexico is a boundary called ¿la frontera¿ where developing and developed worlds meet, resulting in a unique, hybrid environment in nearly every aspect of life. This area is a melting pot, combining the unique challenges to human health from each side of the border into a region of double jeopardy, with the population at risk from the ills of both environments. The higher than normal rates in El Paso of neurocystercercosis and drug resistant TB are two examples of the result of this juxtaposition. The increased development of the desert regions of West Texas exacerbate this problem, bringing increasing numbers of people into frequent contact with new environments, enhancing the opportunity for the spread of new diseases. Because of these concerns, the Border Biomedical Research Center at the University of Texas at El Paso includes a specific research unit in Infectious Diseases to foster the development of research programs on infectious agents of regional importance. In addition to continuing support of existing research programs, this proposal equipment and staff support infrastructure for a new BSL3 laboratory research facility included in the new Biosciences Research Building at UTEP. This secure facility will enable development of research programs focussing on higher level infectious agents, in particular drug resistant Mycobacterium tuberculo