Function of Flightless I in the skin blistering disorder epidermolysis bullosa

皮肤起泡疾病是痛苦和衰弱。它们可能导致永久性疤痕，并可能在出生后两年内危及生命。没有具体的治疗方法。我们以前的研究已经确定了Flii在伤口愈合中的重要作用。我们现在的目标是研究Flii在皮肤起泡疾病中的潜在功能。我们还将确定调节Flii是否减少水疱形成。这项研究可能会为治疗皮肤脆弱的人带来新的疗法。

Skin blistering disorders are painful and debilitating. They can lead to permanent scarring and may be life threatening within two years of birth. No specific cure exists. Our previous studies have identified the important role of Flii in wound healing. We now aim to investigate the potential function of Flii in skin blistering disorders. We will also determine whether modulating Flii reduces blister formation. This research could lead to new therapies for treating people with fragile skin.