Cancer Research Center of Hawaii

描述(申请人提供)：夏威夷癌症研究中心(CRCH)是NCI指定的临床癌症中心。CRCH在癌症研究、教育、社区推广和病人护理方面承担着多种责任。它是夏威夷州唯一的这样的机构。夏威夷为癌症提供了独特的研究机会，这在美国或世界其他地方都是无与伦比的。夏威夷独特的研究机会的基础是该州人口的种族和文化多样性及其地理位置和独特环境。CRCH的研究工作分为三个研究项目：癌症病因学、预防和控制以及天然产品和癌症生物学。所有这三个研究计划都特别利用夏威夷多民族人口为基础、基于人口和临床研究提供的生物多样性，以及热带生物圈的自然多样性来进行药物发现。在CCSG当前的资助周期中，这三个项目都取得了重大的科学进展。从1999年至今，已在800多种国际文献出版物中取得并传播了令人振奋和新颖的研究成果。CRCH还运营着夏威夷肿瘤注册中心，这是美国12个SEER注册中心之一，太平洋癌症信息服务中心，以及一个向夏威夷癌症患者提供约150项临床试验的大型临床试验单位。在当前的CCSG周期中，CRCH的支持研究空间几乎翻了一番，其中包括将于2005年年中完工的一座新研究大楼，面积约为50,000平方英尺。此外，正在计划建造一座约350,000平方英尺的新癌症中心大楼，该大楼不仅将为当前的研究项目提供扩展设施，还将包括一个与该州最大的医院合作提供全面癌症护理服务的现代化门诊设施。这些发展将允许在未来建立一个强大的临床研究活动。

DESCRIPTION (provided by applicant): The Cancer Research Center of Hawaii (CRCH) is an NCI-designated Clinical Cancer Center. CRCH has diverse responsibility in cancer research, education, community outreach, and patient care. It is the only such institution in the State of Hawaii. Hawaii offers special research opportunities for cancer that are unparalleled elsewhere in the country or the world. The basis for the unique research opportunities in Hawaii are the ethnic and cultural variety of the State's population as well as its geographic location and unique environment. Research efforts at CRCH are organized into three research programs: Cancer Etiology, Prevention and Control, and Natural Products and Cancer Biology. All three research programs take particular advantage of the biodiversity offered by the multiethnic population of Hawaii for basic, population-based, and clinical studies as well as by the natural diversity of the tropical biosphere for drug discovery. All three programs have made significant scientific progress during the current CCSG funding cycle. Exciting and novel research results have been obtained and disseminated in over 800 publications in the international literature from 1999 until today. CRCH also operates the Hawaii Tumor Registry, one of 12 SEER registries in the country, the Cancer Information Service-Pacific, and a large Clinical Trials Unit which makes approximately 150 clinical trials available to Hawaii's cancer patients. Over the current cycle of CCSG support research space at CRCH approximately doubled, including approximately 50,000 square feet in a new research building to be completed by mid-2005. Furthermore, plans are underway to construct a new Cancer Center building of approximately 350,000 square feet which will not only provide expanded facilities for current research programs, but will include a modern outpatient care facility offering comprehensive cancer care services in partnership with the largest hospitals in the State. These developments will allow to build a strong clinical research activity in the future.