CONSORTIUM FOR THE LONGITUDINAL EVALUATION OF AFRICAN AMERICANS WITH EA (CLEAR)

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究的目的是建立一个患有早期类风湿性关节炎的非裔美国人的登记。这是第一个对一大批非裔美国人进行系统纵向研究的早期类风湿性关节炎登记。登记将包括总共500名患者，他们将在5年的病程中进行评估。为了达到500人的目标，将招募多达600名患者。登记的主要目的之一是从患者血液样本中分离和永生基因组DNA，以供未来研究使用。皮特曼GCRC处理、存储和分离通过该登记处获得的所有基因组DNA。GCRC信息学核心作为数据库储存库，使用TeleForm和其他数据管理能力来管理登记册数据。在报告所述期间，共有9名患者入选，在此期间，OMB正在等待豁免状态。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to create a registry of African Americans with early rheumatoid arthritis. This is the first early rheumatoid arthritis registry in which a large cohort of African Americans is systematically studied in a longitudinal fashion. The registry will include a total of 500 patients who will be evaluable at 5 years disease duration. To obtain the goal of 500, as many as 600 patients will be enrolled. One of the primary aims of the registry is to isolate and immortalize genomic DNA from patient blood samples for use in future studies. The Pittman GCRC processes, stores, and isolates all genomic DNA obtained through this registry. The GCRC Informatics Core serves as the database repository using Teleform and other data management capabilities to manage the registry data. A total of 9 patients were enrolled in the reporting period, during which exemption status was pending from the OMB.